本文關(guān)鍵詞：益精杞菊地黃顆粒劑對(duì)早期青光眼視神經(jīng)保護(hù)的臨床觀察，由筆耕文化傳播整理發(fā)布。

益精杞菊地黃顆粒劑對(duì)早期青光眼視神經(jīng)保護(hù)的臨床觀察

Clinical observation of Yijing Qiju Dihuang granules of early glaucomatous optic protection

[1] [2] [3] [4] [5]

LIU Jian,ZHANG Lixia,LIU Jie,et al（Ophthalmology Departmerit, Eye Hospital of China Academy of Chinese Medical Sciences, Beijing 100040, China）

[1]中國(guó)中醫(yī)科學(xué)院眼科醫(yī)院眼科,北京100040; [2]青海大學(xué),西寧810016

文章摘要：目的：觀察益精杞菊地黃顆粒劑對(duì)眼壓控制的早期青光眼視野的影響。方法2014年2月—2015年6月在我院門診就診的眼壓控制的早期青光眼患者60例（120只眼），包括原發(fā)性開角型青光眼、原發(fā)性閉角型青光眼及正常眼壓性青光眼患者。隨機(jī)分為治療組及對(duì)照組。治療組30例（60只眼），予口服服用益精杞菊地黃顆粒劑（杞菊地黃丸加減方）；對(duì)照組30例（60只眼），予口服腺苷鉆胺片。2組均連續(xù)用藥3個(gè)月，觀察2組治療前后的視野變化。結(jié)果治療后3個(gè)月，，2組受試者視野的平均光敏感度（MS）、平均缺損（MD）及丟失方差（LV）數(shù)值均較治療前改善（P＜0.05），但各指標(biāo)變化值的組間差異無(wú)統(tǒng)計(jì)學(xué)意義（P＞0.05）。視野療效評(píng)價(jià)：治療組視野改善25只眼，穩(wěn)定35只眼，惡化0只眼，視野改善率41.7%；對(duì)照組視野改善24只眼，穩(wěn)定36只眼，惡化0只眼，視野改善率40.0%，2組改善率差異無(wú)統(tǒng)計(jì)學(xué)意義（c2=0.034，P=0.853）。2組受試者治療后的視力均未見明顯變化。結(jié)論益精杞菊地黃顆粒劑與腺苷鈷胺對(duì)于早期青光眼視野損害均有改善作用，且作用相當(dāng)。

Abstr：OBJECTIVE To observe the effect of＆nbsp;Yijing Qiju Dihuang granules on early glaucomatous visual field of intraocular pressure control. METHODS In our hospital outpatient from February 2014-June 2015, IOP controlled early glaucoma patients （60cases, 120 eyes）, including primary open-angle glaucoma, primary angle-closure glaucoma and normal glaucoma patients were ran-domly divided into treatment group and control group. Treatment group, 30 patients （60 eyes）, was given oral ad-ministration to Yijing Qiju Dihuang granules （Qijudihuang Pill）;control group of 30 patients （60 eyes）, to oral adenosine amine drill sheet. Two groups were on medication for three months, and were observed field changes before and after treatment. RESULTS Three months after treatment, two groups’ mean sensitivity （MS）, mean defect （MD） and loss variance （LV） value improved than that before treatment （P〈0.05）, but changes in the value of each index had no significant difference （P〉0.05）. Evaluation Vision：therapy group 25 eyes improved, 35 eyes steady and 0 eye deteriorated, vision improvement rate was 41.7%;control group, 24 eyes improved, stable 36 eyes, and 0 eye deteriorated, vision improvement rate was 40.0%. Improvement rate of the two groups showed no significant dif-ference （c2=0.034, P=0.853）. Vision of the 2 groups after treatment showed no significant changes. CONCLU-SIONS Yijing Qiju Dihuang granules and adenosylcobalamin had played a considerable role for early glaucoma vi-sual field damage.

文章關(guān)鍵詞：

Keyword：:Chinese medicine glaucoma neuroprotection

作者信息：會(huì)員可見

  本文關(guān)鍵詞：益精杞菊地黃顆粒劑對(duì)早期青光眼視神經(jīng)保護(hù)的臨床觀察，由筆耕文化傳播整理發(fā)布。