【摘要】：目的探討孤立性腦橋梗死急性期神經(jīng)功能缺損進(jìn)展的預(yù)測(cè)因素。方法收集發(fā)病48 h內(nèi)經(jīng)DWI證實(shí)的138例孤立性腦橋梗死患者的臨床資料,據(jù)卒中發(fā)生后病情最嚴(yán)重時(shí)NIHSS評(píng)分變化(NIHSS評(píng)分較入院增加≥2分或運(yùn)動(dòng)障礙評(píng)分增加≥1分)分為急性期神經(jīng)功能缺損進(jìn)展組(進(jìn)展組)和非進(jìn)展組。比較兩組的危險(xiǎn)因素、實(shí)驗(yàn)室檢查及影像學(xué)檢查特征,采用Logistics回歸分析急性期神經(jīng)功能缺損進(jìn)展的預(yù)測(cè)因素。結(jié)果單因素分析顯示,進(jìn)展組空腹血糖、入院時(shí)NIHSS評(píng)分、出院時(shí)的mRS評(píng)分明顯高于非進(jìn)展組(P0.05)。進(jìn)展組累及腦橋腹側(cè)表面梗死、梗死灶最大直徑、重度腦室旁WMH及皮質(zhì)下WMH明顯高于非進(jìn)展組(P0.05)。Logistic回歸分析顯示累及腦橋腹側(cè)表面梗死(OR=0.160,95%CI:0.052~0.493,P=0.001)、重度腦室旁WMH(OR=2.824,95%CI:1.206~6.614,P=0.017)及重度皮質(zhì)下WMH(OR=3.460,95%CI:1.427~8.393,P=0.006)是孤立性腦橋梗死急性期神經(jīng)功能缺損進(jìn)展的獨(dú)立危險(xiǎn)因素。結(jié)論累及腦橋腹側(cè)表面梗死及重度WMH是孤立性腦橋梗死急性期神經(jīng)功能缺損進(jìn)展的預(yù)測(cè)因素。
[Abstract]:Objective to investigate the predictors of neurological deficit in acute stage of isolated pontine infarction. Methods the clinical data of 138 patients with isolated pontine infarction confirmed by DWI within 48 hours after stroke were collected. According to the changes of NIHSS score (NIHSS score 鈮，

本文編號(hào)：2525705