【摘要】：目的探討孤立性腦橋梗死急性期神經功能缺損進展的預測因素。方法收集發(fā)病48 h內經DWI證實的138例孤立性腦橋梗死患者的臨床資料,據卒中發(fā)生后病情最嚴重時NIHSS評分變化(NIHSS評分較入院增加≥2分或運動障礙評分增加≥1分)分為急性期神經功能缺損進展組(進展組)和非進展組。比較兩組的危險因素、實驗室檢查及影像學檢查特征,采用Logistics回歸分析急性期神經功能缺損進展的預測因素。結果單因素分析顯示,進展組空腹血糖、入院時NIHSS評分、出院時的mRS評分明顯高于非進展組(P0.05)。進展組累及腦橋腹側表面梗死、梗死灶最大直徑、重度腦室旁WMH及皮質下WMH明顯高于非進展組(P0.05)。Logistic回歸分析顯示累及腦橋腹側表面梗死(OR=0.160,95%CI:0.052~0.493,P=0.001)、重度腦室旁WMH(OR=2.824,95%CI:1.206~6.614,P=0.017)及重度皮質下WMH(OR=3.460,95%CI:1.427~8.393,P=0.006)是孤立性腦橋梗死急性期神經功能缺損進展的獨立危險因素。結論累及腦橋腹側表面梗死及重度WMH是孤立性腦橋梗死急性期神經功能缺損進展的預測因素。
[Abstract]:Objective to investigate the predictors of neurological deficit in acute stage of isolated pontine infarction. Methods the clinical data of 138 patients with isolated pontine infarction confirmed by DWI within 48 hours after stroke were collected. According to the changes of NIHSS score (NIHSS score 鈮，

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