心電圖QRS波時(shí)限延長(zhǎng)與老年高血壓合并心力衰竭血清N末端腦鈉肽前體及近期預(yù)后的相關(guān)性
發(fā)布時(shí)間:2019-06-28 19:50
【摘要】:目的探討心電圖QRS波時(shí)限延長(zhǎng)與老年高血壓合并心力衰竭血清N末端腦鈉肽前體(NT-pro BNP)及近期預(yù)后的相關(guān)性。方法選取2015年2月—2016年4月浙江寧波大學(xué)醫(yī)學(xué)院附屬醫(yī)院收治的177例老年高血壓合并心力衰竭為研究對(duì)象,按照出院后隨訪6個(gè)月的是否發(fā)生主要心臟不良事件(MACE)分為MACE組(n=55)及非MACE組(n=122),按照入院時(shí)的QRS波時(shí)限分為QRS波時(shí)限≤120 ms組(n=113),QRS波時(shí)限120 ms組(n=64),收集兩組入院時(shí)的一般臨床資料,比較兩組的差異;利用Pearson相關(guān)分析QRS波時(shí)限與NT-pro BNP以及相關(guān)心功能指標(biāo)的相關(guān)性,并利用Logistic回歸方程分析QRS波時(shí)限與近期預(yù)后的關(guān)系。結(jié)果與非MACE組比較,MACE組左心室射血分?jǐn)?shù)(LVEF)較低、收縮壓(SBP)、舒張壓(DBP)、左心室質(zhì)量指數(shù)(LVMI)、血清尿酸、空腹血糖(FPG)、NT-pro BNP水平升高,QRS波時(shí)限QTcd延長(zhǎng),差異有統(tǒng)計(jì)學(xué)意義(P0.05)。與QRS波時(shí)限≤120 ms組比較,QRS波時(shí)限120 ms組LVEF降低,而LVMI、NT-pro BNP水平、MACE發(fā)生率較高(P0.05);Pearson相關(guān)分析顯示QRS波時(shí)限與NT-pro BNP呈正相關(guān)(r=0.352,P0.05);Logistic回歸分析提示QRS波時(shí)限延長(zhǎng)是老年高血壓合并心力衰竭患者近期發(fā)生MACE的獨(dú)立危險(xiǎn)因素[OR=1.942,95%CI(1.260,2.839)]。結(jié)論 QRS波時(shí)限延長(zhǎng)與老年高血壓合并心力衰竭患者血清NT-pro BNP以及不良預(yù)后具有相關(guān)性,可能是患者預(yù)后不良的獨(dú)立預(yù)測(cè)因素,臨床應(yīng)當(dāng)引起醫(yī)師的關(guān)注。
[Abstract]:Objective to investigate the relationship between the prolongation of QRS wave and serum N-terminal brain natriuretic peptide precursor (NT-pro BNP) and short-term prognosis in elderly patients with hypertension complicated with heart failure. Methods from February 2015 to April 2016, 177 elderly patients with hypertension complicated with heart failure were divided into MACE group (n 鈮,
本文編號(hào):2507567
[Abstract]:Objective to investigate the relationship between the prolongation of QRS wave and serum N-terminal brain natriuretic peptide precursor (NT-pro BNP) and short-term prognosis in elderly patients with hypertension complicated with heart failure. Methods from February 2015 to April 2016, 177 elderly patients with hypertension complicated with heart failure were divided into MACE group (n 鈮,
本文編號(hào):2507567
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