144例感染性心內(nèi)膜炎臨床及病原學(xué)特點(diǎn)分析
發(fā)布時(shí)間:2019-05-22 20:32
【摘要】:目的分析北京大學(xué)第一醫(yī)院近10年感染性心內(nèi)膜炎(infective endocarditis,IE)患者的臨床及病原學(xué)特點(diǎn)。方法回顧性分析2006年至2015年144例IE患者的臨床資料,包括人口學(xué)資料、臨床表現(xiàn)和實(shí)驗(yàn)室檢查結(jié)果以及微生物學(xué)檢查結(jié)果。結(jié)果全組患者以男性為主(2.3∶1),平均年齡46.6歲。最為常見的合并心臟疾病為先天性心臟病(22.9%),其次為退行性心瓣膜病(18.8%);合并風(fēng)濕性心臟病的患者比例僅為10.4%。最常見的臨床表現(xiàn)為發(fā)熱(91.7%),其次為心臟雜音(90.3%)和貧血(76.4%)。最常見受累的心臟瓣膜為二尖瓣(40.3%)及主動(dòng)脈瓣(39.6%)。右心瓣膜受累的IE患者均為先天性心臟病患者。在87例血培養(yǎng)陽性的IE患者中,草綠色鏈球菌占55.2%,為最常見的致病菌。分離出的鏈球菌屬細(xì)菌對青霉素G的敏感率為94.1%;葡萄球菌屬細(xì)菌占24.1%,其中甲氧西林耐藥葡萄球菌屬細(xì)菌比例38.1%。結(jié)論 IE患者合并先天性心臟病和退行性心瓣膜病的比例已經(jīng)超過風(fēng)濕性心臟病。草綠色鏈球菌仍是我國IE患者的主要病原菌。
[Abstract]:Objective to analyze the clinical and etiological characteristics of infective endocarditis (infective endocarditis,IE) in the first Hospital of Peking University in recent 10 years. Methods the clinical data of 144 patients with IE from 2006 to 2015 were analyzed retrospectively, including demographic data, clinical manifestations, laboratory findings and microbiological results. Results the patients were mainly male (2.3 鈮,
本文編號:2483237
[Abstract]:Objective to analyze the clinical and etiological characteristics of infective endocarditis (infective endocarditis,IE) in the first Hospital of Peking University in recent 10 years. Methods the clinical data of 144 patients with IE from 2006 to 2015 were analyzed retrospectively, including demographic data, clinical manifestations, laboratory findings and microbiological results. Results the patients were mainly male (2.3 鈮,
本文編號:2483237
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