【摘要】：目的分析飲酒對OSAS患者睡眠結(jié)果及睡眠結(jié)構(gòu)的影響。方法對260例2015年8月至2016年9月就診于新疆維吾爾自治區(qū)高血壓中心的高血壓患者,采用回顧性問卷調(diào)查所有研究對象的飲酒史,根據(jù)飲酒分組標(biāo)準(zhǔn),最后我們把入選人群分為少量飲酒組病人(91)、大量飲酒組病人(79)、非飲酒組病人(93)。以AHI及LSaO2嚴(yán)重程度分組比較OSAS患者睡眠參數(shù)及睡眠結(jié)構(gòu)的變化。結(jié)果1.對260例病人根據(jù)飲酒程度比較發(fā)現(xiàn):非飲酒的病人、少量飲酒的病人及大量飲酒的病人的生化資料、AHI、LSa O2以及睡眠結(jié)構(gòu)差別均無統(tǒng)計學(xué)意義(P0.05)。2.進(jìn)一步以AHI嚴(yán)重程度分組:AHI≥15病人中,非飲酒的病人、少量飲酒的病人及大量飲酒的病人的AHI、LSaO2以及睡眠結(jié)構(gòu)沒有差別(P0.05);AHI15病人中,非飲酒的病人、少量飲酒的病人及大量飲酒的病人的AHI、LSaO2、睡眠2期存在差異(P0.05)。3.以LSa O2嚴(yán)重程度分組:LSaO280%病人中,非飲酒的病人、少量飲酒的病人及大量飲酒的病人的AHI、LSaO2未見差異(P0.05),但三組病人的睡眠2期存在差異(P0.05);LSa O2≥80%病人中,非飲酒組病人、少量飲酒組病人與大量飲酒組病人的LSaO2存在差異(P0.05),三組病人的AHI無統(tǒng)計學(xué)意義,并且發(fā)現(xiàn)三組病人的睡眠2期、睡眠3期、睡眠4期之間存在統(tǒng)計學(xué)差異(P0.05)。結(jié)論飲酒對AHI15及LSaO2≥80%的病人的AHI、LSaO2以及睡眠結(jié)構(gòu)影響更加顯著,而對AHI≥15及LSaO280%的病人的AHI、LSaO2以及睡眠結(jié)構(gòu)影響無明顯差異�？赡苁芑颊叩哪挲g及肥胖程度的影響掩蓋了酒精的作用,因為發(fā)現(xiàn)在AHI15次/分及LSaO280%分組中,年齡及BMI都具有統(tǒng)計學(xué)差異。而眾多的研究表明,肥胖和年齡也是導(dǎo)致OSAS加重的重要因素。
[Abstract]:Objective to analyze the effects of alcohol drinking on sleep outcome and sleep structure in OSAS patients. Methods 260 patients with hypertension from August 2015 to September 2016 in Xinjiang Uygur Autonomous region were investigated with a retrospective questionnaire. Finally, we divided the selected population into a small drinking group (91), a heavy drinking group (79), and a non-drinking group (93). The changes of sleep parameters and sleep structure in OSAS patients were compared by AHI and LSaO2 severity groups. Outcome 1. The results showed that there was no significant difference in biochemical data, AHI,LSa O2 and sleep structure between non alcohol drinker, small alcohol drinker and heavy alcohol drinker according to the degree of drinking (P0.05). According to the severity of AHI, there was no significant difference in AHI,LSaO2 and sleep structure among patients with AHI 鈮，

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