【摘要】：目的探討血流儲(chǔ)備分?jǐn)?shù)(FFR)在冠脈臨界病變介入治療中的指導(dǎo)作用。方法選擇該院行冠狀動(dòng)脈造影(CAG)明確狹窄程度為70%~90%且擬行經(jīng)皮冠狀動(dòng)脈介入治療(PCI)的患者98例,依據(jù)治療方法分為中觀察組(51例)和對(duì)照組(47例)。觀察組每處病變均行FFR測(cè)定,僅在FFR≤0.80處行支架植入,對(duì)照組常規(guī)CAG檢查后行PCI。記錄兩組術(shù)中平均支架植入數(shù)量、造影劑使用量和手術(shù)時(shí)間,術(shù)后隨訪12個(gè)月統(tǒng)計(jì)不良心血管事件發(fā)生情況。結(jié)果觀察組平均支架植入數(shù)量、造影劑使用量和手術(shù)時(shí)間均低于對(duì)照組(P0.05)。術(shù)后12個(gè)月兩組再發(fā)心絞痛、心肌梗死、再次血運(yùn)重建和心源性死亡發(fā)生率差異均無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論對(duì)于冠狀動(dòng)脈臨界病變,FFR為選擇性進(jìn)行PCI治療提供參考,能夠減少平均支架植入數(shù)量、造影劑使用量和手術(shù)時(shí)間,節(jié)省醫(yī)療費(fèi)用,減少了支架植入和造影劑使用相關(guān)并發(fā)癥的發(fā)生風(fēng)險(xiǎn)。
[Abstract]:Objective to investigate the guiding role of (FFR) in the interventional therapy of coronary critical lesions. Methods Ninety-eight patients who underwent coronary angiography (CAG) with a definite stenosis of 70% and planned percutaneous coronary intervention (PCI) were divided into two groups according to the treatment methods: the middle observation group (51 cases) and the control group (47 cases). In the observation group, FFR was measured for each lesion, and stent implantation was performed only at FFR 鈮，

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