宣痹通脈湯聯(lián)合美托洛爾對急性心肌梗死后早期心室重構(gòu)和心臟功能的影響
發(fā)布時間:2018-08-03 07:17
【摘要】:目的:研究宣痹通脈湯聯(lián)合美托洛爾對急性心肌梗死(AMI)后早期心室重構(gòu)和心臟功能的影響。方法:納入本院96例AMI患者隨機(jī)分組,48例給予美托洛爾治療者歸為對照組,48例給予宣痹通脈湯+美托洛爾治療者歸為治療組,治療4周。比較兩組療效,治療前后中醫(yī)證候積分、左心室參數(shù)、心功能、心肌鈣蛋白(c TnⅠ)和氨基前端腦鈉肽(Nt-pro BNP)變化。結(jié)果:治療組治療總有效率91.67%,對照組75%,差異具有統(tǒng)計學(xué)意義(P0.05);治療后,兩組胸痛、胸悶、心悸、眩暈、乏力、氣短積分均顯著降低,左室射血分?jǐn)?shù)(LVEF)、左室舒張末期容積(LVEDV)、左室收縮末期容積(LVESV)顯著上升,左心室舒張末內(nèi)徑(LVEDD)顯著下降,每搏輸出量(SV)、心臟指數(shù)(CI)顯著提升,心功能顯著提升,且治療組提升或降低幅度大于對照組,差異具有統(tǒng)計學(xué)意義(P0.05);治療后,兩組c TnⅠ和Nt-pro BNP水平顯著下降,且治療組下降幅度大于對照組,差異具有統(tǒng)計學(xué)意義(P0.05)。結(jié)論:宣痹通脈湯聯(lián)合美托洛爾可顯著改善AMI患者臨床證候表現(xiàn),改善早期心室重構(gòu)和提升心功能,減小心肌梗死面積,療效顯著,值得臨床推廣。
[Abstract]:Aim: to study the effects of Xuanbi Tongmai decoction combined with metoprolol on early ventricular remodeling and cardiac function after acute myocardial infarction (AMI). Methods: 96 patients with AMI in our hospital were randomly divided into two groups: 48 patients treated with metoprolol were divided into control group and 48 patients treated with metoprolol with Xuanbi Tongmai decoction for 4 weeks. The changes of TCM syndromes, left ventricular parameters, cardiac function, cardiac troponin (c Tn 鈪,
本文編號:2161011
[Abstract]:Aim: to study the effects of Xuanbi Tongmai decoction combined with metoprolol on early ventricular remodeling and cardiac function after acute myocardial infarction (AMI). Methods: 96 patients with AMI in our hospital were randomly divided into two groups: 48 patients treated with metoprolol were divided into control group and 48 patients treated with metoprolol with Xuanbi Tongmai decoction for 4 weeks. The changes of TCM syndromes, left ventricular parameters, cardiac function, cardiac troponin (c Tn 鈪,
本文編號:2161011
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