【摘要】：目的:了解非瓣膜病心房顫動患者生活質(zhì)量情況及左心耳封堵術(shù)對其生活質(zhì)量的變化有無影響。方法:選取東南大學附屬中大醫(yī)院2014年9月至2016年6月心內(nèi)科住院期間的非瓣膜病房顫患者100例為房顫組(其中11例行經(jīng)皮穿刺左心耳封堵術(shù)),同期東南大學附屬中大醫(yī)院門診體檢的非心房顫動人群100例為對照組,使用漢密爾頓焦慮/抑郁量表(HAMA/HAMD)和美國簡明健康測試量表(SF-36)對入選對象進行評分,11例左心耳封堵術(shù)患者在術(shù)后3個月再次進行生活質(zhì)量評分。數(shù)據(jù)采用SPSS 13.0軟件分析。結(jié)果:(1)房顫組患者八個維度生活質(zhì)量相關評分比對照人群低(63.04土8.51vs.69.72±7.69、58.25± 18.14vs.69.70± 15.12、66.10± 12.52vs.71.30土 12.18、57.95土 13.91 vs.66.25士 12.78、55.65±11.93vs.62.40±12.28、68.69±14.85vs.75.80±11.09、67.69土21.94vs.72.36±15.74、70.86±15.90vs.77.96±9.56),其中七個維度差異有統(tǒng)計學意義(p0.05)。(2)房顫組中存在焦慮或抑郁情緒的患者占42%,對照組中存在焦慮或抑郁情緒的患者占7%,兩組比較有明顯差異(p0.05)。(3)合并焦慮/抑郁的心房顫動患者較單純心房顫動患者八個維度生活質(zhì)量評分更低(65.40±8.48vs.59.79土7.50、62.93±17.04vs.51.79±16.92、69.05±12.90vs.62.02±10.88、62.14土13.97vs.54.91±13.12、58.79±12.82vs.51.43±8.92、72.05±14.15vs.64.57士14.79、72.44±19.87vs.62.72±22.34、74.28±16.04vs.66.14±14.63),差異有統(tǒng)計學意義(p0.05)。(4)行左心耳封堵的非瓣膜病心房顫動患者術(shù)后三個月八個維度生活質(zhì)量評分較術(shù)前升高(59.09±6.89vs.61.82±7.26、54.55±15.08vs.75.00±15.81、62.27 ±6.47vs.68.64±6.74、63.18±10.31vs.68.64±8.69、51.36±8.97vs.67.27±8.47、73.76±12.46vs.86.89±4.49、75.78±15.55vs.78.81±16.80、76.36±6.31vs85.46±8.63),其中五個維度有顯著升高(p0.05)。結(jié)論:非瓣膜病心房顫動患者較非心房顫動人群焦慮、抑郁障礙發(fā)生率高,總體生活質(zhì)量低,合并焦慮/抑郁障礙的心房顫動患者生活質(zhì)量更低。左心耳封堵術(shù)可改善非瓣膜病心房顫動患者生活質(zhì)量。
[Abstract]:Objective: to investigate the quality of life (QOL) in patients with non-valvular atrial fibrillation (NAF) and the effect of left atrial appendage closure (LASA) on the quality of life (QOL). Methods: from September 2014 to June 2016, 100 patients with non-valvular fibrillation were selected as atrial fibrillation group (11 of them underwent percutaneous transcatheter closure of left atrial appendage). 100 cases of non-atrial fibrillation patients who were examined in outpatient clinic of the middle and large hospitals were the control group. The Hamilton anxiety / Depression scale (HAMA/HAMD) and the American brief Health Test scale (SF-36) were used to evaluate the quality of life in 11 patients with left atrial ear occlusion. The data were analyzed by SPSS 13.0 software. 緇撴灉:(1)鎴塊ⅳ緇勬?zhèn)ｈ�呭叓涓淮搴︾敓媧昏川閲忕浉鍏寵瘎鍒嗘瘮瀵圭収浜虹兢浣，

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