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老年冠心病患者PCI術(shù)后不良心臟事件危險因素分析

發(fā)布時間:2018-07-03 19:08

  本文選題:冠狀動脈粥樣硬化性心臟病 + 經(jīng)皮冠狀動脈介入治療術(shù)。 參考:《山東醫(yī)藥》2017年04期


【摘要】:目的探討老年冠心病患者經(jīng)皮冠狀動脈介入治療(PCI)術(shù)后發(fā)生不良心臟事件的危險因素。方法回顧297例老年冠心病PCI術(shù)后患者的臨床資料,包括性別、年齡、BMI、文化程度、住院次數(shù)、合并高血壓、合并糖尿病、合并高血脂、飲酒史、吸煙史、家族遺傳史、運動情況以及隨訪期間不良心臟事件(心絞痛復(fù)發(fā)、心肌梗死、嚴(yán)重心律失常、心源性死亡)發(fā)生情況。采用SPSS20.0統(tǒng)計軟件,以性別、年齡、BMI、文化程度、住院次數(shù)、合并高血壓、合并糖尿病、合并高血脂、飲酒史、吸煙史、家族遺傳史、運動情況為自變量,PCI術(shù)后不良心臟事件為因變量,先對各影響因素與PCI術(shù)后不良心臟事件發(fā)生情況的關(guān)系行單因素Logistic回歸分析,對其中差異有統(tǒng)計學(xué)意義的因素行多因素Logistic回歸分析。結(jié)果本組患者隨訪期間88例(29.63%)出現(xiàn)不良心臟事件,單因素Logistic回歸分析結(jié)果表明,年齡、合并糖尿病、合并高血壓、合并高血脂、飲酒史、吸煙史、家族遺傳史、運動與老年冠心病患者PCI后發(fā)生不良心臟事件有關(guān)(P均0.05)。多因素Logistic回歸分析結(jié)果顯示,合并糖尿病OR為12.324,95%CI為5.124~32.663;吸煙OR為10.483,95%CI為4.856~20.219;合并高血壓OR為8.542,95%CI為4.856~20.219;合并高血脂OR為8.158,95%CI為1.732~12.633;家族遺傳史OR為7.824,95%CI為1.532~10.073;年齡≥65歲OR為6.021,95%CI為1.341~8.334。結(jié)論合并糖尿病、吸煙、合并高血壓史、合并高血脂、家族遺傳史、年齡超過65歲是老年冠心病患者PCI術(shù)后不良心臟事件的危險因素。
[Abstract]:Objective to investigate the risk factors of adverse cardiac events after percutaneous coronary intervention (PCI) in elderly patients with coronary heart disease. Methods the clinical data of 297 elderly patients with coronary heart disease after PCI were retrospectively reviewed, including sex, age, education, frequency of hospitalization, hypertension, diabetes mellitus, hyperlipidemia, alcohol consumption, smoking history, family genetic history. Exercise and adverse cardiac events (recurrence of angina pectoris, myocardial infarction, severe arrhythmia, cardiac death) during follow-up. SPSS 20.0 software was used to analyze sex, age BMIs, education, hospitalization times, hypertension, diabetes mellitus, hyperlipidemia, alcohol consumption, smoking history, family genetic history. Exercise condition was independent variable and adverse cardiac events after PCI were dependent variables. Univariate logistic regression analysis was performed to analyze the relationship between the influencing factors and adverse cardiac events after PCI. Multivariate logistic regression analysis was performed for the factors with statistical significance. Results 88 patients (29.63%) had adverse cardiac events during the follow-up period. Univariate logistic regression analysis showed that age, diabetes mellitus, hypertension, hyperlipidemia, alcohol consumption, smoking history, family genetic history. Exercise was associated with adverse cardiac events in elderly patients with coronary heart disease (P 0.05). The results of multivariate logistic regression analysis showed that the OR of diabetes mellitus was 5.124 鹵32.663, OR of smoking was 10.483,95CI was 4.856 鹵20.219, OR of hypertension was 8.542.95CI was 4.85620.219, OR of hyperlipidemia was 8.15895CI was 1.73212.633, the genetic history of family was 7.824995 CI was 1.53210.073; the OR of age 鈮,

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