本文選題：心肌梗死 + 白細(xì)胞　； 參考：《首都醫(yī)科大學(xué)學(xué)報》2017年03期

【摘要】：目的探討白細(xì)胞計數(shù)與急性ST段抬高型心肌梗死(ST-segment elevation myocardial infarction,STEMI)病人直接經(jīng)皮冠狀動脈介入術(shù)(percutaneous coronary intervention,PCI)中無復(fù)流的關(guān)系。方法選取2013年11月至2015年12月因急性STEMI住院并行直接PCI的病人266例,根據(jù)PCI術(shù)中無復(fù)流發(fā)生情況分為正常復(fù)流組(A組)242例和無復(fù)流組(B組)24例。比較兩組病人臨床資料特點及住院期間主要不良心血管事件(major adverse cardiovascular events,MACE)發(fā)生率,采用Logistic回歸分析篩選急性STEMI病人PCI術(shù)中無復(fù)流的影響因素。結(jié)果無復(fù)流組白細(xì)胞計數(shù)、血肌酐明顯高于正常復(fù)流組(P0.05),Killip≥3級比例顯著升高(P=0.009);兩組病人住院期間MACE發(fā)生率分別為16.7%和2.9%(P=0.001)。多因素Logistic回歸分析結(jié)果顯示白細(xì)胞計數(shù)(OR=1.220,95%CI:1.064~1.399,P=0.004)、Killip分級(OR=4.617,95%CI:1.093~2.095,P=0.037)是急性STEMI病人PCI術(shù)中無復(fù)流的獨立預(yù)測因素。結(jié)論入院時白細(xì)胞計數(shù)是急性STEMI病人PCI術(shù)中無復(fù)流的獨立預(yù)測因素,早期檢測白細(xì)胞計數(shù)可以初步評估PCI術(shù)中無復(fù)流的發(fā)生風(fēng)險。
[Abstract]:Objective to investigate the relationship between leukocyte count and non-reflow in patients with ST-segment elevation myocardial infarction (ST-segment elevation myocardial inflexion) undergoing direct percutaneous coronary intervention (PCI). Methods from November 2013 to December 2015, 266 patients underwent direct PCI due to acute STEMI were divided into two groups: normal reflow group (n = 242) and non-reflow group (n = 24). The characteristics of clinical data and the incidence of major adverse cardiovascular events during hospitalization were compared between the two groups. Logistic regression analysis was used to screen the influencing factors of no reflow in acute STEMI patients. Results the white blood cell count in no reflow group was significantly higher than that in the normal reflow group (P 0.05 Killip 鈮，

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