發(fā)布時間：2018-06-03 23:00

  本文選題：血清尿酸 + 原發(fā)性高血壓　； 參考：《中華高血壓雜志》2017年06期

【摘要】：目的探討血清尿酸與高血壓患者左心室肥厚(LVH)的關系,以及這種關系在男女之間是否存在差異。方法選擇福建省級機關醫(yī)院原發(fā)性高血壓患者2140例,根據(jù)血清尿酸水平四分位數(shù)分組,比較4組的左心室質(zhì)量指數(shù)(LVMI)和左心室肥厚(LVH)發(fā)生率;按男、女分層,比較男、女尿酸四分位組間LVMI和LVH發(fā)生率的差異;采用多因素Logistic回歸分析男、女患者尿酸與LVH發(fā)生的關系。結(jié)果隨著尿酸四分位水平遞增,女性患者LVMI和LVH發(fā)生率逐漸增加[分別為(114.41±34.51),(121.34±36.98),(126.86±42.52),(141.74±46.36)g/m2;35.0%,47.0%,52.1%,61.7%;均P0.05],而男性患者4組間LVMI差異有統(tǒng)計學意義[分別為(144.12±76.44),(132.58±40.39),(134.24±41.00),(141.84±55.02)g/m2;P0.05],LVH發(fā)生率差異無統(tǒng)計學意義(57.1%,50.2%,54.3%,52.7%;P0.05)。和女性相比,男性尿酸、LVMI升高,LVH發(fā)生率增加(均P0.05)。Logistic回歸分析顯示,尿酸是女性患者中LVH發(fā)生的獨立危險因素[OR(95%CI)=1.30(1.13~1.56),P0.01],男性患者中尿酸與LVH的相關性無統(tǒng)計學意義(P0.05)。結(jié)論盡管女性高血壓患者尿酸及LVH程度較男性低,但女性患者尿酸與LVH相關,而男性患者這種相關性無統(tǒng)計學意義。
[Abstract]:Objective To investigate the relationship between serum uric acid and left ventricular hypertrophy ( LVMI ) in patients with hypertension , and whether there was any difference between men and women . The incidence of LVMI and LVMI in male and female patients was significantly increased according to serum uric acid level . Results The incidence of LVMI in female patients was significantly higher than that in male and female patients ( 144.12 鹵 76.44 ) , ( 132.58 鹵 40.39 ) , ( 134.24 鹵 41.00 ) , ( 144.84 鹵 55.02 ) g / m2 , P0.05 and P0.05 ) . Logistic regression analysis showed that uric acid was the independent risk factor ( OR ( 95 % CI ) = 1.30 ( 1.13 锝，

本文編號：1974590