本文選題：西尼地平 + 交感神經(jīng)興奮性��； 參考：《中國臨床藥理學(xué)雜志》2017年17期

【摘要】：目的觀察西尼地平片治療原發(fā)性高血壓的臨床療效及安全性。方法80例原發(fā)性高血壓患者在服用西尼地平之前,每天早晨起床后(每天的同一時(shí)間)在家測量血壓和心率,連續(xù)測量3 d并且記錄,作為基線值。服用西尼地平后每2,4,8周復(fù)診并記錄血壓和心率,療程8周。比較基線值與西尼地平治療后血壓、心率的變化。結(jié)果治療前、治療2,4,8周后,診室收縮壓分別為(171.94±21.02),(148.19±11.28),(127.20±7.28),(126.98±7.52)mm Hg;舒張壓分別為(97.91±15.27),(86.44±9.76),(77.85±6.87),(76.10±6.61)mm Hg;診室心率分別為(76.31±9.72),(72.26±7.28),(70.01±6.22),(69.91±6.11)次/分;家庭收縮壓分別為(170.13±18.98),(148.37±10.57),(127.52±7.30),(127.00±7.44)mm Hg,家庭舒張壓分別為(97.20±12.59),(86.65±9.26),(77.95±6.63),(77.58±6.42)mm Hg;家庭心率分別為(76.05±9.17),(72.15±7.05),(69.98±6.15),(69.88±6.04)次/分;西尼地平治療原發(fā)性高血壓的有效率為88.89%(64/72例),差異均有統(tǒng)計(jì)學(xué)意義(均P0.05)。治療過程中,頭暈2例、低血壓1例、面部潮紅1例、潮熱1例、心悸1例,藥物不良反應(yīng)發(fā)生率為7.5%(6/80例)。結(jié)論西尼地平可以有效降低原發(fā)性高血壓患者的血壓和心率。
[Abstract]:Objective to observe the efficacy and safety of cilnidipine tablets in the treatment of essential hypertension. Methods the blood pressure and heart rate of 80 patients with essential hypertension were measured at home after getting up every morning (at the same time every day) before taking cilnidipine for 3 days and recorded as the baseline value. Blood pressure and heart rate were recorded 8 weeks after taking cilnidipine for 8 weeks. To compare the baseline value with the changes of blood pressure and heart rate after treatment with cilnidipine. 緇撴灉娌葷枟鍓，

本文編號(hào)：1944221