本文選題：老年高血壓 + 糖尿病��； 參考：《昆明醫(yī)科大學(xué)》2015年碩士論文

【摘要】：目的：分析單純老年原發(fā)性高血壓與老年原發(fā)性高血壓合并糖尿病兩類患者并發(fā)頸動(dòng)脈粥樣硬化及粥樣硬化斑塊回聲強(qiáng)度的差異,評(píng)估此差異對(duì)指導(dǎo)頸動(dòng)脈粥樣硬化的早期預(yù)防、療效評(píng)估及預(yù)后的臨床意義。方法：選取老年原發(fā)性高血壓患者共161例,年齡65-95歲,男性87例,女性74例。所有納入患者按照是否患有糖尿病分為2組,A組：老年高血壓伴有糖尿病患者43例,其中37例伴頸動(dòng)脈粥樣硬化斑塊的形成；B組：?jiǎn)渭兝夏旮哐獕航M118例,其中108例伴頸動(dòng)脈粥樣硬化斑塊的形成。分別采集兩組患者的性別、年齡、患高血壓年限、體重指數(shù)、平均靜息心率、動(dòng)態(tài)血壓、晝夜節(jié)律、肝腎功能、空腹血糖、血脂、頸動(dòng)脈超聲、頸動(dòng)脈粥樣硬化斑塊回聲強(qiáng)度等資料進(jìn)行比較,并分析兩組患者頸動(dòng)脈粥樣硬化斑塊回聲強(qiáng)度的影響因素。結(jié)果：①兩組患者一般資料比較結(jié)果,差異均無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)；②兩組患者比較,頸動(dòng)脈粥樣硬化的形成,差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)；③兩組患者比較,A組患者頸動(dòng)脈粥樣硬化斑塊回聲強(qiáng)度低于B組患者,差異有統(tǒng)計(jì)學(xué)意義(P0.01)；④兩組患者比較,A組患者空腹血糖較B組患者高,高密度脂蛋白膽固醇較B組患者低,差異有統(tǒng)計(jì)學(xué)意義(P0.01)；⑤患者性別與動(dòng)脈粥樣硬化硬斑、軟斑的形成有相關(guān)性,差異有統(tǒng)計(jì)學(xué)意義(P0.05);結(jié)論：1.老年高血壓合并糖尿病患者頸動(dòng)脈粥樣硬化斑塊回聲強(qiáng)度較低,相對(duì)不穩(wěn)定。2.頸動(dòng)脈粥樣硬化的形成在單純老年高血壓和老年高血壓合并糖尿病兩組患者間無(wú)明顯差異。3.頸動(dòng)脈粥樣硬化斑塊的回聲強(qiáng)度與血糖升高、高密度脂蛋白膽固醇降低有關(guān)。4.男性患者比女性患者更容易形成軟斑。
[Abstract]:Objective: to analyze the difference of echo intensity of carotid atherosclerosis and atherosclerotic plaque between elderly essential hypertension and elderly essential hypertension with diabetes mellitus. To evaluate the clinical significance of this difference in early prevention, therapeutic evaluation and prognosis of carotid atherosclerosis. Methods: 161 elderly patients with essential hypertension, aged 65-95 years, 87 males and 74 females were selected. All patients were divided into two groups according to whether or not they had diabetes: 43 elderly patients with hypertension accompanied by diabetes, 37 patients with carotid atherosclerotic plaque formation, 118 patients with simple elderly hypertension, 108 cases of carotid atherosclerotic plaque formation. Sex, age, duration of hypertension, body mass index, mean resting heart rate, ambulatory blood pressure, circadian rhythm, liver and kidney function, fasting blood glucose, blood lipid, carotid ultrasound were collected. The echo intensity of carotid atherosclerotic plaque was compared and the influencing factors of echo intensity of carotid atherosclerotic plaque in two groups were analyzed. Results there was no significant difference in general data between the two groups. There was no significant difference in the formation of carotid atherosclerosis between the two groups. The echo intensity of carotid atherosclerotic plaque in group A was lower than that in group B, and there was significant difference between group A and group B, and the fasting blood glucose in group A was higher than that in group B. High density lipoprotein cholesterol (HDL-C) was lower in group B than that in group B (P 0.01). There was a significant correlation between sex and atherosclerotic hard spot and soft plaque formation in group B, and the difference was statistically significant (P 0.05). The echo intensity of carotid atherosclerotic plaques in elderly patients with hypertension and diabetes mellitus is low, relatively unstable. 2. 2. There was no significant difference in carotid atherosclerosis between the elderly hypertension group and the elderly hypertension with diabetes group. 3. 3. The echo intensity of carotid atherosclerotic plaques is associated with increased blood glucose and decreased high density lipoprotein cholesterol. Men are more likely to develop soft spots than women.
【學(xué)位授予單位】：昆明醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2015
【分類號(hào)】：R544.1;R587.1

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本文編號(hào)：1939234