本文選題：甲狀腺激素 + 甲狀腺功能　； 參考：《重慶醫(yī)科大學(xué)》2017年碩士論文

【摘要】：心房纖顫動是常見的心律失常之一,甲狀腺功能狀態(tài)與房顫息息相關(guān)。心臟是甲狀腺激素重要的靶器官之一,甲狀腺激素能夠通過其基因效應(yīng)及非基因效應(yīng)調(diào)控心臟的結(jié)構(gòu)及功能。異常的甲狀腺功能改變其生理性效應(yīng),從而影響心臟的結(jié)構(gòu)功能,可促進房顫的發(fā)生及維持。大型臨床試驗研究顯示甲狀腺功能亢進患者更容易發(fā)生心房顫動,甲亢動物模型的房顫可誘導(dǎo)性及持續(xù)性均明顯增加,表明甲亢是房顫的高危因素。就目前已有研究顯示,甲狀腺功能減退是否增加額外的房顫風(fēng)險仍存在爭議,但在接受心臟手術(shù)的患者中,甲狀腺功能減退可增加術(shù)后發(fā)生房顫的風(fēng)險。房顫可引起致殘、致死性腦血管意外,而甲狀腺功能狀態(tài)可影響機體凝血功能,從而改變房顫患者栓塞風(fēng)險,在診療活動更為強調(diào)保持正常的甲狀腺功能水平。
[Abstract]:Atrial fibrillation is one of the common arrhythmias. Thyroid function is closely related to atrial fibrillation. The heart is one of the important target organs of thyroid hormone. Thyroid hormone can regulate the structure and function of heart through its gene effect and non-gene effect. Abnormal thyroid function changes its physiological effect, thus affecting the cardiac structure and function, which can promote the occurrence and maintenance of atrial fibrillation. Large clinical trials showed that patients with hyperthyroidism were more likely to develop atrial fibrillation, and the induced and persistent atrial fibrillation in hyperthyroidism animal model were significantly increased, indicating that hyperthyroidism was a high risk factor for atrial fibrillation. Whether hypothyroidism increases the risk of atrial fibrillation remains controversial, but in patients undergoing cardiac surgery, hypothyroidism may increase the risk of postoperative AF. Atrial fibrillation can cause disability, fatal cerebrovascular accident, and thyroid function can affect the coagulation function of the body, thus changing the risk of embolism in patients with atrial fibrillation, and more emphasis on maintaining normal thyroid function level in diagnosis and treatment activities.
【學(xué)位授予單位】：重慶醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R541.75

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本文編號：1911161