本文選題：心外膜脂肪組織 + 冠心病��； 參考：《復(fù)旦學(xué)報(醫(yī)學(xué)版)》2017年01期

【摘要】：目的評價心外膜脂肪組織(epicardial adipose tissue,EAT)體積與冠心病的存在及嚴(yán)重度的相關(guān)性。方法納入同期行64排CT(computed tomography,CT)冠狀動脈成像及經(jīng)皮冠狀動脈造影的疑似冠心病患者201例。通過CT測量EAT體積和冠狀動脈鈣化積分(coronary artery calcium,CAC)。根據(jù)冠脈造影結(jié)果進(jìn)行CAGE≥20、CAGE≥50及Gensini評分,再根據(jù)評分確定冠心病的程度和嚴(yán)重性。通過統(tǒng)計學(xué)方法分析EAT體積值與冠心病的相關(guān)性。結(jié)果根據(jù)冠狀動脈造影結(jié)果分為正常組(108例)及冠心病組(93例)。冠心病組EAT體積平均值明顯大于正常組[(135.36±45.36)cm3vs.(88.56±40.64)cm3],兩組相比差異有顯著統(tǒng)計學(xué)意義(P=0.004),而體質(zhì)量指數(shù)(BMI)及腰圍(WC)在兩組間無統(tǒng)計學(xué)差異。在多因素Logistic回歸分析中,在調(diào)整了年齡、性別、吸煙、飲酒以及BMI因素后,EAT體積與冠心病和CAC顯著相關(guān)(P=0.009)。在線性回歸分析中,EAT體積與CAGE≥20、CAGE≥50和Gensini評分顯著相關(guān)(P0.05)。并且隨著EAT體積的增加,冠心病的嚴(yán)重程度隨之增加(P0.05)。結(jié)論 EAT體積與冠心病的存在和嚴(yán)重程度相關(guān)。EAT可以作為冠心病風(fēng)險的預(yù)測因子。
[Abstract]:Objective to evaluate the correlation between the volume of epicardial adipose tissue (epicardial adipose tissue) and the presence and severity of coronary heart disease (CHD). Methods Sixty-four rows of coronary angiography and percutaneous coronary angiography were performed simultaneously in 201 patients with suspected coronary artery disease. EAT volume and coronary artery calcification score were measured by CT. According to the results of coronary angiography, the CAGE 鈮，

本文編號：1905941