發(fā)布時間：2018-05-18 00:23

  本文選題：元胞自動機 + 跨膜電位�。� 參考：《物理學(xué)報》2017年20期

【摘要】：建立了包含心房肌、心室肌、房室腔、室間隔并考慮心室肌分層結(jié)構(gòu)的心電圖元胞自動機模型.利用所建立的模型,仿真了電信號在心臟中的傳導(dǎo),計算了正常和缺血情況下的場點電勢走勢.數(shù)值結(jié)果表明:正常情況下,模擬所得的場點電勢呈現(xiàn)與標準心電圖一致的P波、QRS波群、T波和J波;在心內(nèi)膜下肌細胞缺血情況下,出現(xiàn)T波倒置的現(xiàn)象;在心外膜下肌細胞缺血情況下,T波變得高聳;在透壁缺血情況下,T波提前形成,QT間期縮短.將正常和異常情況下的場點電勢走勢與臨床結(jié)果進行了對比,并分析了其形成與持續(xù)機制.研究結(jié)果可為準確闡明心電圖與心肌細胞電活動之間的關(guān)系、探討心電圖的產(chǎn)生與持續(xù)機制提供參考.
[Abstract]:An electrocardiogram (ECG) cellular automata model including atrial, ventricular, atrioventricular, interventricular septum and delamination of ventricular muscle was established. Using the established model, the conduction of electrical signals in the heart is simulated, and the field potential trends under normal and ischemic conditions are calculated. The numerical results show that, under normal conditions, the simulated field potential shows P wave QRS wave group T wave and J wave in accordance with the standard electrocardiogram, and T wave inversion occurs under the condition of subendocardial muscle cell ischemia. In the case of subpericardial myocyte ischemia, T wave became towering, and the T wave formed earlier and the QT interval shortened under the condition of transmural ischemia. The field potential trend under normal and abnormal conditions is compared with the clinical results and the mechanism of its formation and persistence is analyzed. The results can provide a reference for clarifying the relationship between electrocardiogram (ECG) and cardiomyocyte electrical activity and to explore the mechanism of electrocardiogram (ECG) generation and persistence.
【作者單位】： 廣西師范大學(xué)物理科學(xué)與技術(shù)學(xué)院;
【基金】：國家自然科學(xué)基金(批準號:11365003,11565005,11647309)資助的課題~~
【分類號】：R540.41

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