本文選題：隱匿性冠心病 + 心肌梗塞　； 參考：《天津醫(yī)科大學(xué)》2017年碩士論文

【摘要】：目的:以隱匿性冠心病患者病灶多發(fā)與單發(fā)代表病灶體積大小來分析隱匿性冠心病患者病灶體積對(duì)心肌舒縮功能的影響。探究核素心肌血流灌注顯像和平衡門控法心血池顯像在隱匿性冠心病診斷中的價(jià)值。方法:本課題研究對(duì)象選取了38例隱匿性冠心病患者及23名陳舊性心肌梗死病史患者。以上患者均進(jìn)行核素心肌血流灌注顯像觀察左心室各部分室壁放射性變化,而后進(jìn)行平衡門控法心血池顯像以獲得心肌功能的定量分析參數(shù),包括高峰射血率(PER)、高峰充盈率(PFR)、左室射血分?jǐn)?shù)(LVEF)、高峰充盈時(shí)間(TPFR)及局部射血分?jǐn)?shù)(REF)、局部室壁軸縮短率(RS)。對(duì)上述心肌功能參數(shù)進(jìn)行分析時(shí),首先進(jìn)行隱匿性冠心病組與心肌梗死組的對(duì)比分析,然后對(duì)隱匿性冠心病組按照病灶單發(fā)與多發(fā)分組進(jìn)而進(jìn)行病灶單發(fā)組與多發(fā)組的對(duì)比分析,統(tǒng)計(jì)學(xué)采用SPSS Statistics 19.0統(tǒng)計(jì)學(xué)分析軟件,分析方法為獨(dú)立樣本t檢驗(yàn),P0.05為差異有統(tǒng)計(jì)學(xué)意義。結(jié)果:核素心肌血流灌注成像顯示隱匿性冠心病組表現(xiàn)為可逆性的放射性缺損,心肌梗死組表現(xiàn)為不可逆的放射性缺損,即為固定性缺損,缺損范圍均局限在部分室壁。隱匿性冠心病組與心肌梗死組的對(duì)比中,門控法心室功能顯像獲得的各項(xiàng)心功能參數(shù)上,左室射血分?jǐn)?shù)、高峰射血速率和高峰充盈速率的差別均具有顯著的統(tǒng)計(jì)學(xué)意義(P0.01);隱匿性冠心病病灶單發(fā)組與多發(fā)組的對(duì)比中,左室射血分?jǐn)?shù)的差別有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:隱匿性冠心病組及心肌梗死組核素心肌血流灌注成像分別表現(xiàn)為可逆性的放射性缺損及固定性放射缺損,缺損范圍均局限在部分室壁。因此,這兩種疾病可根據(jù)核素心肌血流灌注成像的檢查結(jié)果相互鑒別。隱匿性冠心病對(duì)心肌的損害明顯低于心肌梗死,隱匿性冠心病病灶多發(fā)對(duì)心肌舒縮功能損害高于單發(fā),即病灶體積對(duì)心肌的舒縮功能損害存在影響。
[Abstract]:Aim: to analyze the effect of volume of occult coronary heart disease on myocardial systolic and diastolic function. To explore the value of radionuclide myocardial perfusion imaging and balanced gated cardiac blood pool imaging in the diagnosis of occult coronary heart disease. Methods: 38 patients with occult coronary heart disease and 23 patients with old myocardial infarction history were selected. The radionuclide myocardial perfusion imaging was performed to observe the changes of left ventricular wall radioactivity, and then the quantitative parameters of myocardial function were obtained by balanced gated blood pool imaging. These include peak ejection rate, peak filling rate, left ventricular ejection fraction (LVEF), peak filling time (TPFR), local ejection fraction (REFN), and local ventricular wall shortening rate (RSV). When analyzing the above mentioned myocardial function parameters, the comparative analysis was made between the occult coronary heart disease group and the myocardial infarction group. Then the patients with occult coronary heart disease were divided into single focus group and multiple group according to the lesion, and then the single focus group and the multiple group were compared and analyzed. SPSS Statistics 19.0 software was used to analyze the statistics. The analysis method was independent sample t test (P 0.05), the difference was statistically significant. Results: radionuclide myocardial perfusion imaging showed reversible radioactive defect in patients with occult coronary heart disease and irreversible radioactive defect in myocardial infarction group. Left ventricular ejection fraction (LVEF) was measured by gated ventricular function imaging in patients with occult coronary heart disease (CHD) and myocardial infarction (MI). The difference of peak ejection rate and peak filling rate was significant (P 0.01), and the difference of left ventricular ejection fraction was significant in the single and multiple groups of occult coronary heart disease. Conclusion: the radionuclide myocardial perfusion imaging in the occult coronary heart disease group and myocardial infarction group showed reversible radiation defect and fixed radiation defect respectively, and the defect scope was limited to part of the ventricular wall. Therefore, the two diseases can be distinguished by radionuclide myocardial perfusion imaging. The myocardial damage of occult coronary heart disease was significantly lower than that of myocardial infarction, and the damage of myocardial systolic and diastolic function was higher than that of occult coronary heart disease, that is, the volume of lesion had an effect on myocardial systolic and diastolic function damage.
【學(xué)位授予單位】：天津醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R541.4;R816.2

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 賈宇恒;鮑海華;;右心功能影像學(xué)評(píng)價(jià)方法的研究進(jìn)展[J];現(xiàn)代臨床醫(yī)學(xué);2015年04期

2 曾國飛;方正;郭大靜;張波莉;陳婷;;對(duì)比研究320排動(dòng)態(tài)容積CT與3.0 T MRI、超聲心動(dòng)圖評(píng)價(jià)左心室功能的臨床價(jià)值[J];臨床放射學(xué)雜志;2012年12期

3 孔德紅;舒先紅;姚豪華;潘翠珍;程蕾蕾;董麗莉;;實(shí)時(shí)三維超聲心動(dòng)圖評(píng)價(jià)正常人右心室節(jié)段容積和收縮功能的研究[J];中華臨床醫(yī)師雜志(電子版);2012年24期

4 蔣健;牛娟琴;葉建軍;劉光耀;韓月東;馬強(qiáng)華;;左心功能評(píng)價(jià)影像學(xué)研究進(jìn)展[J];中國臨床醫(yī)學(xué)影像雜志;2012年11期

5 梁曉麓;劉梅;丁桂春;簡文豪;;實(shí)時(shí)三維超聲心動(dòng)圖對(duì)右心功能的評(píng)價(jià)[J];中華醫(yī)學(xué)超聲雜志(電子版);2012年03期

6 沈浩霖;郭薇;;超聲心動(dòng)圖評(píng)價(jià)右心室功能[J];醫(yī)學(xué)綜述;2010年19期

7 趙洪剛;李小東;張遵城;董華;郭永濤;;老年男性陳舊性心肌梗死左心室舒縮功能變化的特點(diǎn)[J];天津醫(yī)科大學(xué)學(xué)報(bào);2010年03期

8 岳湘竹;鄭蘭蘭;于紅;段海;賈春紅;;脈沖多普勒Tei指數(shù)在評(píng)價(jià)肺動(dòng)脈高壓患者右心室功能中的價(jià)值[J];中國誤診學(xué)雜志;2009年05期

9 劉炯;高桂珠;張寶牛;;門控心肌顯像與超聲心動(dòng)圖、心血池顯像測(cè)定LVEF的對(duì)比研究[J];臨床醫(yī)藥實(shí)踐;2009年01期

10 管琰;楊磊;陳勇軍;潘翠珍;;聲學(xué)定量技術(shù)在評(píng)價(jià)心肌梗死患者左室功能中的價(jià)值[J];浙江醫(yī)學(xué);2007年09期

相關(guān)碩士學(xué)位論文 前3條

1 蘇倩;基于逐步回歸分析的隱匿性冠心病整體泵功能影響因素研究[D];天津醫(yī)科大學(xué);2015年

2 譚厚敏;256層螺旋CT與磁共振成像評(píng)價(jià)左心功能的對(duì)比研究[D];復(fù)旦大學(xué);2011年

3 趙洪剛;無癥狀心肌缺血心臟功能學(xué)特征的核素顯像研究[D];天津醫(yī)科大學(xué);2010年

，

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