本文選題：心力衰竭 + 心肌病�。� 參考：《中國(guó)循環(huán)雜志》2017年05期

【摘要】：目的:回顧性分析16例接受心臟再同步化治療(CRT)的擴(kuò)張期肥厚型心肌病患者的臨床特征及療效。方法:2007-03至2016-01期間16例符合適應(yīng)證的擴(kuò)張期肥厚型心肌病患者在阜外醫(yī)院接受CRT,回顧性分析其臨床特征及療效。結(jié)果:16例患者中,男性12例,女性4例;平均年齡(53.3±13.5)歲;術(shù)前心電圖平均QRS時(shí)限為(158.7±32.2)ms;左心室射血分?jǐn)?shù)(LVEF)為(33.6±6.3)%;紐約心臟協(xié)會(huì)(NYHA)心功能分級(jí)Ⅰ~Ⅳ級(jí)的例數(shù)分別為1例、5例、8例和2例;新安裝CRT裝置者13例,升級(jí)者3例;合并心房顫動(dòng)患者8例。平均隨訪(2.56±2.13)年,共5例患者死亡,其中3例死于心力衰竭,1例猝死,1例死于卒中。6個(gè)月隨訪時(shí),7例患者對(duì)CRT有反應(yīng)(定義為:NYHA心功能分級(jí)改善≥1級(jí)且LVEF絕對(duì)值提高≥5%);NYHA心功能分級(jí)從(2.69±0.79)級(jí)改善為(2.38±0.89)級(jí)(P=0.02);LVEF從(33.6±6.3)%提高到(40.03±9.83)%(P=0.01)。結(jié)論:符合CRT適應(yīng)證的擴(kuò)張期肥厚型心肌病患者中,心房顫動(dòng)的患病率更高,傳統(tǒng)起搏器或者埋藏式心律轉(zhuǎn)復(fù)除顫器升級(jí)為CRT的患者較多。接受CRT的擴(kuò)張期肥厚型心肌病患者總體預(yù)后較差,但仍有一定比例的患者對(duì)CRT有反應(yīng)。
[Abstract]:Objective: to retrospectively analyze the clinical characteristics and curative effect of 16 patients with dilated hypertrophic cardiomyopathy who received cardiac resynchronization therapy (CRT). Methods Sixteen patients with dilated hypertrophic cardiomyopathy from March 2007 to January 2016 were treated with CRT in Fuwai Hospital. The clinical features and efficacy of CRT were analyzed retrospectively. Results among the 16 patients, 12 were male and 4 were female, with an average age of 53.3 鹵13.5years. The mean QRS duration of preoperative ECG was 158.7 鹵32.2 Ms, left ventricular ejection fraction (LVEF) was 33.6 鹵6.3, cardiac function grade 鈪，

本文編號(hào)：1802451