本文選題：高血壓 + Klotho蛋白　； 參考：《中國地方病防治雜志》2017年05期

【摘要】：目的 S探討Klotho蛋白、一氧化氮(NO)、內(nèi)皮素(ET-1)在高血壓發(fā)生發(fā)展中的作用機(jī)制。方法高血壓患者120例為觀察組,另選健康體檢者40例為對(duì)照組,觀察組根據(jù)血壓水平分為觀察A組(高血壓I期)40例、觀察B組(高血壓Ⅱ期)40例及觀察C組(高血壓Ⅲ期)40例,均行血清Klotho蛋白、NO、ET-1水平檢測(cè)。結(jié)果血清Klotho蛋白、NO水平與血壓呈負(fù)相關(guān)。與對(duì)照組比較,觀察組各組血清NO水平均較低,觀察B、C組血清Klotho蛋白水平較低(P0.05);ET-1隨血壓水平與血壓呈正相關(guān)。觀察B、C組ET-1水平較對(duì)照組高(P0.05)。結(jié)論血清Klotho蛋白、NO、ET-1水平與血壓密切相關(guān),可能為誘發(fā)高血壓發(fā)生的原因之一。
[Abstract]:Objective to investigate the role of Klotho protein, nitric oxide (no) and endothelin (et-1) in the development of hypertension.Methods 120 patients with hypertension were selected as observation group and 40 healthy persons as control group. According to the blood pressure level, the observation group was divided into two groups: group A (40 cases).The serum levels of Klotho protein (NON-ET-1) were measured in 40 patients in group B (hypertension stage 鈪，

本文編號(hào)：1756569