發(fā)布時(shí)間：2018-04-15 04:05

  本文選題：舒張性心力衰竭 + 保元湯��； 參考：《中國(guó)老年學(xué)雜志》2017年15期

【摘要】：目的探討保元湯聯(lián)合參麥注射液治療老年舒張性心力衰竭(DHF)的療效及對(duì)血漿腦鈉肽(BNP)和舒張功能的影響。方法老年DHF患者80例按照隨機(jī)數(shù)字表法分為試驗(yàn)組和對(duì)照組各40例。兩組均給予常規(guī)西藥治療,試驗(yàn)組再給予保元湯聯(lián)合參麥注射液治療。對(duì)比兩組治療效果,并且應(yīng)用免疫熒光法(IFA)檢測(cè)治療前后血漿BNP水平,使用超聲檢測(cè)左室舒張功能和左室射血分?jǐn)?shù)(LVEF)變化。結(jié)果試驗(yàn)組治療總有效率顯著高于對(duì)照組(P0.05);治療后兩組LVEF水平均升高,且試驗(yàn)組高于對(duì)照組。血漿BNP水平明顯降低,且試驗(yàn)組低于對(duì)照組(P0.05);治療后兩組舒張?jiān)缙诔溆俣?E)、E/舒張晚期充盈速度(A)均升高,且試驗(yàn)組均高于對(duì)照組A、減速時(shí)間(DT)均降低,低于對(duì)照組(P0.05)。結(jié)論保元湯聯(lián)合參麥注射液治療老年DHF效果顯著,可以明顯降低血漿BNP水平,改善左室舒張功能,值得臨床推薦。
[Abstract]:Objective to investigate the efficacy of Baoyuan decoction combined with Shenmai injection in the treatment of elderly patients with diastolic heart failure (DHF) and its effects on plasma brain natriuretic peptide (BNP) and diastolic function.Methods 80 elderly patients with DHF were randomly divided into trial group and control group.Both groups were treated with routine western medicine, and the experimental group were treated with Baoyuan decoction combined with Shenmai injection.The plasma BNP levels, left ventricular diastolic function and left ventricular ejection fraction (LVEF) were measured by immunofluorescence before and after treatment.Results the total effective rate in the experimental group was significantly higher than that in the control group (P 0.05), and the level of LVEF in the two groups increased after treatment, and was higher in the experimental group than in the control group.Plasma BNP level was significantly lower in the experimental group than that in the control group (P 0.05), and the early diastolic filling velocity and the late diastolic filling velocity in the two groups were increased after treatment, and both in the test group were higher than those in the control group, and the deceleration time was lower than that in the control group (P 0.05).Conclusion Baoyuan decoction combined with Shenmai injection is effective in the treatment of senile DHF, which can significantly reduce plasma BNP level and improve left ventricular diastolic function, which is worthy of clinical recommendation.
【作者單位】： 鄭州市第九人民醫(yī)院心臟中心;鄭州市第九人民醫(yī)院老年一科;鄭州市第九人民醫(yī)院內(nèi)分泌代謝科;
【分類號(hào)】：R541.6

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