本文選題：正常高值收縮壓 + 全因死亡�。� 參考：《中華高血壓雜志》2017年07期

【摘要】：目的探討正常高值收縮壓與人群全因死亡的關(guān)系。方法采用前瞻性隊(duì)列研究方法,以首次參加2006-2007、2008-2009年開(kāi)灤集團(tuán)健康體檢的職工作為觀察對(duì)象。進(jìn)行統(tǒng)一問(wèn)卷調(diào)查、體格測(cè)量和生化檢查,以發(fā)生全因死亡為終點(diǎn)事件。根據(jù)《中國(guó)高血壓防治指南2010》血壓水平分類(lèi)標(biāo)準(zhǔn),將2006-2007年和2008-2009年第1次參加體檢的人群按收縮壓分為3組:120mm Hg組(n=32 412)、120~130mm Hg組(n=23 822)、130~140mm Hg組(n=12 543),共68 777人。用壽命表法計(jì)算全人群、男性及女性人群的累積全因死亡率,并采用Cox比例風(fēng)險(xiǎn)模型分析正常高值收縮壓對(duì)全人群、男性及女性人群全因死亡的影響。結(jié)果平均隨訪(7.39±1.14)年,全人群3組累積全因死亡率分別為2.85%、3.99%、6.19%;男性人群分別為3.72%、4.68%、6.83%;女性人群分別為0.90%、1.14%、2.88%。多因素Cox比例風(fēng)險(xiǎn)回歸模型分析顯示,校正全部混雜因素后,以收縮壓120mm Hg組為對(duì)照,全人群120~130mm Hg和130~140mm Hg組發(fā)生全因死亡風(fēng)險(xiǎn)比(95%CI)分別為1.13(1.01~1.28)和1.24(1.09~1.42);男性分別為1.16(1.02~1.31)和1.23(1.07~1.41);女性分別0.82(0.52~1.29)和1.47(0.92~2.35);青、中、老年120~130mm Hg和130~140mm Hg組發(fā)生全因死亡風(fēng)險(xiǎn)比(95%CI)分別為1.55(0.86~2.78)和1.64(0.77~3.49);1.24(1.04~1.48)和1.38(1.12~1.71);1.00(0.84~1.18)和1.10(0.93~1.30)。結(jié)論正常高值收縮壓能夠增加人群全因死亡的風(fēng)險(xiǎn),男性人群和中年人群風(fēng)險(xiǎn)更為顯著。
[Abstract]:Objective to investigate the relationship between normal high systolic blood pressure and total death.Methods A prospective cohort study was used to observe the health examination of the workers who first participated in the physical examination of Kailuan Group from 2006 to 2007 to 2008-2009.A uniform questionnaire survey, physical examination and biochemical examination were conducted to end with all-cause death.According to the classification standard of blood pressure level of China Hypertension Prevention and treatment Guide 2010, the people who took part in the first physical examination in 2006-2007 and 2008-2009 were divided into 3 groups according to systolic blood pressure (SBP). They were divided into 3 groups (n = 23 822 ~ 140 mm Hg, n = 68 777) according to systolic blood pressure (SBP).The cumulative all-cause mortality of the whole population, male and female population was calculated by life table method, and the effect of normal high systolic blood pressure on the whole population, male and female population was analyzed by Cox proportional risk model.Results after an average follow-up of 7.39 鹵1.14 years, the cumulative all-cause mortality of the three groups was 2.85 and 3.996.19, that of the male was 3.72and 4.68, and that of the female was 0.90 and 1.142.88, respectively.Multivariate Cox proportional risk regression model analysis showed that after correcting all confounding factors, systolic blood pressure (120mm Hg) group was used as control.鍏ㄤ漢緹，

本文編號(hào)：1734447