老年心力衰竭患者出院后2年預后及影響因素
發(fā)布時間:2018-03-31 12:20
本文選題:心力衰竭 切入點:再住院率 出處:《臨床心血管病雜志》2017年12期
【摘要】:目的:分析老年心力衰竭患者出院后2年內的預后狀況并探索影響其生存的因素。方法:隨訪觀察146例老年心力衰竭患者出院后2年內再住院或死亡等臨床資料,平均隨訪約15個月。分析患者預后狀況,采用多因素Cox回歸模型分析影響預后的因素。結果:146例患者出院后3、6、9、12、15、18、21、24個月的因心力衰竭再住院率分別為3.4%、10.9%、17.1%、19.2%、22.6%、26.0%、30.1%、35.6%;病死率分別為1.4%、2.7%、3.4%、6.8%、9.6%、12.3%、15.8%、20.5%;Cox回歸分析顯示,年齡75歲的患者發(fā)生再住院或死亡的危險性是≤75歲的2.353倍;氨基末端B型腦鈉肽前體(NT-proBNP)1 000ng/L的患者發(fā)生危險性是NT-proBNP≤1 000ng/L的2.347倍;左室射血分數(shù)(LVEF)≤0.5%的患者發(fā)生危險性是LVEF0.5%的2.105倍;血紅蛋白濃度≤130g/L的患者發(fā)生危險性是血紅蛋白濃度130g/L的1.853倍;不規(guī)律服用β-受體阻滯劑的患者發(fā)生危險性是規(guī)律服用β-受體阻滯劑的1.961倍;不規(guī)律服用利尿劑的患者發(fā)生危險性是規(guī)律服用利尿劑的1.49倍。結論:老年心力衰竭患者2年內的累積再住院及病死率分別為35.6%、20.5%。年齡、NT-proBNP、LVEF、血紅蛋白濃度、β-受體阻滯劑、利尿劑是影響老年心力衰竭患者2年內生存的主要因素。
[Abstract]:Objective: to analyze the prognosis of elderly patients with heart failure within 2 years after discharge and to explore the factors influencing their survival. Methods: 146 elderly patients with heart failure were followed up to observe the clinical data of re-hospitalization or death within 2 years after discharge. The mean follow-up was about 15 months. The multivariate Cox regression model was used to analyze the prognostic factors. Results in 20. 5% patients with heart failure and 20. 5%, 20. 5% had a mortality rate of 2. 4% 2.73.46.86.86% and 20. 5%, respectively, for 24 months. The average readmission rate for 24 months was 3. 4% 10.9% 17. 1% and 19. 2 0% 20. 6%. The mortality rate was 1. 4% 2.73.46.86.89.6% and 12. 315.815.815.815.5x, respectively. The risk of rehospitalization or death in patients aged 75 years was 2.353 times higher than that in patients aged 鈮,
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