發(fā)布時(shí)間：2018-02-04 09:23

  本文關(guān)鍵詞： 經(jīng)皮冠狀動(dòng)脈介入治療 服藥依從性 消化道出血　出處：《中國老年學(xué)雜志》2017年13期 　論文類型：期刊論文

【摘要】：目的探究老年經(jīng)皮冠狀動(dòng)脈介入治療(PCI)術(shù)后患者長(zhǎng)期雙聯(lián)抗血小板的服藥依從性與消化道出血的相關(guān)性。方法篩選進(jìn)行PCI手術(shù)的老年患者300例,采用隨機(jī)數(shù)字表法將其分為三組:A組(n=100)患者術(shù)后服用阿司匹林和氯吡格雷;B組(n=100)患者術(shù)后服用阿司匹林;C組(n=100)患者術(shù)后服用氯吡格雷�；颊叱鲈汉蟮姆幥闆r通過隨訪得到,隨訪時(shí)間為術(shù)后12個(gè)月。隨訪內(nèi)容包括患者服藥是否按照醫(yī)囑,若未按照醫(yī)囑,其停藥時(shí)間和停藥原因以及患者是否出現(xiàn)不良反應(yīng)等情況�；颊叩南狼闆r通過胃鏡進(jìn)行觀察。結(jié)果 A組受試者中依從性好25例,一般17例,差58例;B組受試者中依從性好44例,一般40例,差16例;C組受試者中依從性好36例,一般50例,差14例。A組患者的服藥依存性較差(P0.05)。此外,A組9例,B組4例,C組3例。A組患者的消化道出血比例較B、C組高(P0.05)。老年P(guān)CI術(shù)后患者服藥依從性與患者年齡,付費(fèi)方式呈負(fù)相關(guān),與患者文化程度呈正相關(guān),與患者性別沒有相關(guān)性。結(jié)論老年P(guān)CI術(shù)后患者服藥依從性越差,影響因素較多,應(yīng)有針對(duì)性地做好相關(guān)工作。
[Abstract]:Objective to explore percutaneous coronary intervention (PCI) in elderly patients. The relationship between long-term anti-platelet compliance and gastrointestinal bleeding in patients after operation. Methods 300 elderly patients undergoing PCI operation were selected. The patients were randomly divided into three groups: group 1: group A took aspirin and clopidogrel; Group B (n = 100) took aspirin after operation; Patients in group C took clopidogrel after operation. The status of administration of clopidogrel after discharge was obtained by follow-up for 12 months. The follow-up included whether the drug was taken in accordance with the doctor's instructions. If not according to the doctor's order, the time of withdrawal, the reason of withdrawal and whether the patients had adverse reactions. The digestive tract of the patients were observed by gastroscopy. Results in group A, the compliance was good in 25 cases. General 17 cases, poor 58 cases; In group B, compliance was good in 44 cases, average in 40 cases and poor in 16 cases. In group C, compliance was good in 36 cases, average in 50 cases, poor in group A in 14 cases. In addition, there were 9 cases in group A and 4 cases in group B. The rate of gastrointestinal bleeding in group C was higher than that in group C (P 0.05). There was a negative correlation between drug compliance and age and payment method in elderly patients after PCI. Conclusion the worse the compliance of the elderly patients with PCI, the more influential factors are, and the better the related work should be done.
【作者單位】： 貴航貴陽醫(yī)院心內(nèi)科;北京武警總醫(yī)院心血管內(nèi)科;
【分類號(hào)】：R541.4
【正文快照】： 1北京武警總醫(yī)院心血管內(nèi)科冠心病的致病原因十分復(fù)雜[1~9]。經(jīng)皮冠狀動(dòng)脈介入治療(PCI)是指經(jīng)心導(dǎo)管技術(shù)疏通狹窄甚至閉塞的冠狀動(dòng)脈管腔,從而改善心肌的血流灌注的治療方法,是臨床中治療急性心肌梗死的主要方法[10,11]。目前,臨床中PCI介入路徑包括股動(dòng)脈路徑和橈動(dòng)脈路徑兩

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