本文關(guān)鍵詞： 血清總膽紅素 ST段抬高型心肌梗死 經(jīng)皮冠狀動(dòng)脈介入術(shù) 冠狀動(dòng)脈血流　出處：《中國(guó)老年學(xué)雜志》2017年04期 　論文類(lèi)型：期刊論文

【摘要】：目的探討血清總膽紅素(STB)水平與ST段抬高型心肌梗死患者(STEMI)經(jīng)皮冠狀動(dòng)脈介入治療(PCI)術(shù)后冠狀動(dòng)脈血流的相關(guān)性。方法選取成功實(shí)施PCI的STEMI患者264例,根據(jù)TIMI血流等級(jí)將患者分成兩組,TIMI 0~2組和TIMI 3組。根據(jù)STB水平分成高STB組(0.9 mg/dl)和低STB組(≤0.9 mg/dl),應(yīng)用單因素分析和多因素Logistic回歸分析探討PCI術(shù)后冠狀動(dòng)脈血流的相關(guān)因素。結(jié)果 TIMI 0~2組96例患者平均年齡(61.5±9.7)歲,其中男68例,TIMI 3組患者168例,平均年齡(59.3±10.4)歲,其中男132例;TIMI 0~2組STB水平明顯高于TIMI 3組(P=0.013);院內(nèi)心臟不良事件發(fā)生率明顯高于TIMI 3組(P=0.000 1)。與低STB組相比,高STB水平組無(wú)復(fù)流現(xiàn)象明顯增加(46.0%vs27.5%,P=0.000 9),主要心臟不良事件更加頻繁(19.8%vs 8.7%,P=0.005);多因素Logistic回歸分析,STB水平(OR=2.15,95%CI 1.87~2.52;P=0.002)仍然是影響PCI術(shù)后STEMI患者無(wú)復(fù)流現(xiàn)象發(fā)生的獨(dú)立危險(xiǎn)因素。結(jié)論 STB水平可作為STEMI患者PCI術(shù)后冠狀動(dòng)脈血流恢復(fù)不良的一個(gè)可靠而獨(dú)立的生化標(biāo)記物。
[Abstract]:Objective to investigate the level of serum total bilirubin (STB) and percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI). Methods 264 STEMI patients who successfully performed PCI were selected. Patients were divided into two groups according to TIMI blood flow rating. TIMI 0 group 2 and TIMI group 3 were divided into high STB group (0. 9 mg / dl) and low STB group (鈮，

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