本文關(guān)鍵詞： 高血壓 饑荒年 患病率 危險因素　出處：《青島大學(xué)》2015年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:研究青島地區(qū)高血壓患病率及高血壓的相關(guān)危險因素并分析生命早期遭受食物短缺和營養(yǎng)不良對成年后高血壓患病危險的影響,為社區(qū)高血壓危險因素干預(yù)提供科學(xué)依據(jù)。方法:采用分層和隨機抽樣相結(jié)合的方法在青島市6個區(qū)選取居委會和鄉(xiāng)村,于2006年抽取1953-1970年出生居民3004人,于2009年抽取1953-1970年出生居民3010人,兩次共抽取6014人為調(diào)查對象,收回有效問卷4820份。將1962-1970年出生人群定為非暴露組(N=2501),1959-1961年出生人群定為胚胎期暴露組(N=767),1953-1958年出生人群定為兒童期暴露組(N=1552)。采用SPSS 17.0統(tǒng)計軟件,做單因素和多因素非條件Logistic回歸,分析高血壓相關(guān)危險因素并比較不同組患高血壓危險性。結(jié)果:本次調(diào)查4820名研究對象中,男性1825人,占總?cè)藬?shù)的37.86%。多元線性回歸分析結(jié)果為是否經(jīng)歷大饑荒、年齡、BMI、腰圍、冠心病、高血脂、糖尿病、高血壓家族史、婚姻狀況不良為高血壓發(fā)生的危險因素,女性、經(jīng)濟收入多為高血壓的保護因素。經(jīng)歷過大饑荒的人群高血壓患病率顯著高于未暴露組(P0.01),多因素logistic分析顯示,僅調(diào)整高血壓基本影響因素,兩組的OR(95%CI)為2.078(1.610-2.681)、1.453(1.179-1.792);在上述基礎(chǔ)上再調(diào)整疾病因素,兩組的OR(95%CI)為1.914(1.477-2.480)、1.394(1.127-1.724);最后調(diào)整所有混雜因素,兩組的OR(95%CI)為2.092(1.601-2.734)、1.451(1.165-1.807)。結(jié)論:高血壓是多種因素引起的,生命早期的生活經(jīng)歷,食品短缺和營養(yǎng)不良及其他不利因素可能會增加成年高血壓的風(fēng)險。生命早期的營養(yǎng)問題應(yīng)得到人們的重視,尤其對于社區(qū)婦女及嬰幼兒的營養(yǎng)問題應(yīng)關(guān)注,形成有效的預(yù)防措施來降低成年后各種慢性疾病的發(fā)生率。
[Abstract]:Objective: to study the prevalence and risk factors of hypertension in Qingdao area and to analyze the influence of food shortage and malnutrition in early life on the risk of hypertension in adults. Methods: the method of stratification and random sampling was used to select residents' committees and villages in 6 districts of Qingdao. In 2006, 3,004 residents born 1953-1970 and 3,010 residents born 1953-1970 were drawn on 2009. A total of 6014 subjects were selected and 4820 valid questionnaires were collected. The persons born in 1962-1970 were classified as non-exposed group (n = 2501). Persons born in 1959-1961 were classified as embryonic exposure group (NZ767). People born from 1953 to 1958 were selected as childhood exposure group. SPSS 17.0 statistical software was used to do univariate and multivariate non-conditional Logistic regression. Analysis of risk factors related to hypertension and comparison of the risk of hypertension in different groups. Results: in this study 4820 subjects, 1825 men. The results of multiple linear regression analysis were as follows: a family history of famine, age, waist circumference, coronary heart disease, hyperlipidemia, diabetes, hypertension. Poor marital status is the risk factor of hypertension, female, economic income is the protective factor of hypertension. The prevalence rate of hypertension is significantly higher than that of unexposed group (P0.01). Multivariate logistic analysis showed that the ORQ95 CI of the two groups was 2.0781.6-10-2.681 only adjusted for essential factors of hypertension. 1.453C 1.179-1.792L; On the basis of adjusting the disease factors, the OR 95 CI of the two groups was 1.914 ~ 1.477-2.480 ~ 1.394 ~ 1.127-1.724; Finally, all the confounding factors were adjusted, the ORG95 CI of the two groups was 2.092U 1.601-2.734). Conclusion: hypertension is caused by many factors and early life experience. Food shortages, malnutrition and other adverse factors may increase the risk of adult hypertension. Nutrition problems in early life should be paid attention to, especially for women and infants in the community. Effective prevention measures are developed to reduce the incidence of various chronic diseases in adulthood.
【學(xué)位授予單位】：青島大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2015
【分類號】：R544.1

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