研究背景小腸是人體消化道最長的器官,由于傳統(tǒng)侵襲性檢查手段的限制,如推進(jìn)式內(nèi)鏡（push enteroscopy,PE）只能進(jìn)入近端小腸對小腸病變進(jìn)行診治,結(jié)腸鏡也只能進(jìn)入回腸末端進(jìn)行觀察,因此,既往小腸被認(rèn)為是消化道檢查的盲區(qū)。既往認(rèn)為小腸疾�。╯mall bowel diseases, SBDs）發(fā)病率較低,臨床表現(xiàn)非特異,小腸又位于消化道較深的位置,SBDs的診斷和后續(xù)治療常常被延遲,給SBDs患者造成嚴(yán)重的經(jīng)濟(jì)負(fù)擔(dān)和不良的預(yù)后,這就使得SBDs的早期識(shí)別、診斷和干預(yù)在臨床實(shí)踐中顯得極為重要。隨著膠囊內(nèi)鏡（capsule endoscopy, CE）和氣囊輔助內(nèi)鏡（balloon-assisted enteroscopy, BAE）的臨床應(yīng)用,使得SBDs得以及時(shí)的診斷,同時(shí)又可以獲得小腸粘膜的病理學(xué)診斷,從而使SBDs診治進(jìn)入了一個(gè)新時(shí)代。CE,又稱無線膠囊內(nèi)鏡（wireless CE）,是本世紀(jì)初消化內(nèi)鏡領(lǐng)域一項(xiàng)重大發(fā)明,最初由以色列Given公司研發(fā)和生產(chǎn)。相對于傳統(tǒng)的非侵襲性小腸檢查如利用放射學(xué)檢查的消化道鋇餐、CT, CE能隨自身腸蠕動(dòng)對腸道粘膜進(jìn)行觀察,具有非侵襲性、... 

【文章來源】：南方醫(yī)科大學(xué)廣東省

【文章頁數(shù)】：129 頁

【學(xué)位級(jí)別】：博士

【文章目錄】：
摘要
ABSTRACT
第一部分 雙氣囊小腸鏡對可疑小腸疾病診斷價(jià)值研究
    引言
    資料與方法
    統(tǒng)計(jì)方法
    結(jié)果
    結(jié)論
    討論
    參考文獻(xiàn)
第二部分 雙氣囊小腸鏡和膠囊內(nèi)鏡對Meckel憩室診斷價(jià)值研究
    引言
    資料和方法
    統(tǒng)計(jì)方法
    結(jié)果
    結(jié)論
    討論
    參考文獻(xiàn)
第三部分 雙氣囊小腸鏡和膠囊內(nèi)鏡對小腸間葉組織腫瘤診斷價(jià)值研究
    引言
    資料與方法
    統(tǒng)計(jì)方法
    結(jié)果
    討論
    參考文獻(xiàn)
第四部分 膠囊內(nèi)鏡與CTE/MRI對可疑小腸疾病診斷價(jià)值研究：系統(tǒng)回顧與Meta分析
    引言
    資料與方法
    統(tǒng)計(jì)方法
    結(jié)果
    討論
    參考文獻(xiàn)
全文小結(jié)
縮略語英文對照
攻讀博士期間發(fā)表與待發(fā)表研究
致謝
統(tǒng)計(jì)學(xué)證明


【參考文獻(xiàn)】：
期刊論文
[1]Does capsule endoscopy have an added value in patients with perianal disease and a negative work up for Crohn’s disease?[J]. Samuel N Adler,Metzger Yoav,Scapa Eitan,Chowers Yehuda,Rami Eliakim.  World Journal of Gastrointestinal Endoscopy. 2012(05)
[2]Double-balloon-enteroscopy-based endoscopic retrograde cholangiopancreatography in post-surgical patients[J]. Martin Raithel,Harald Dormann,Andreas Naegel,Frank Boxberger,Eckhart G Hahn,Markus F Neurath,Juergen Maiss.  World Journal of Gastroenterology. 2011(18)
[3]Double-balloon enteroscopy for obscure gastrointestinal bleeding: A single center experience in China[J]. Li-Hua Chen, Wen-Guo Chen, Hong Zhang, Guo-Dong Shan, Lin Li, Bing-Ling Zhang, Cheng-Fu Xu, Guo-Qiang Xu, Department of Gastroenterology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China Hai-Jun Cao, Department of Gastroenterology, First Affiliated Hospital, Zhejiang University of Chinese Medicine, Hangzhou 310003, Zhejiang Province, China Kai-Li Ding, Department of Gastroenterology, Dongyang First People’s Hospital, Jinhua 322100, Zhejiang Province, China Ying Fang, Ying Cheng, Chen-Jiao Wu, Department of Endoscopy Center, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China.  World Journal of Gastroenterology. 2010(13)
[4]Application of double-balloon enteroscopy in the diagnosis and therapy of small intestinal diseases[J]. Department of Gastroenterology,Yantai Yuhuangding Hospital Affiliated to Medical College of Qingdao University,Yantai 264000,China (Wu CR Huang LY Song B Yi LZ Cui J).  Chinese Medical Journal. 2007(23)
[5]Diagnostic procedures for submucosal tumors in the gastrointestinal tract[J]. Laura Graves Ponsaing,Katalin Kiss,Annika Loft,Lise Ingemann Jensen,Mark Berner Hansen.  World Journal of Gastroenterology. 2007(24)
[6]The role of capsule endoscopy combined with double-balloon enteroscopy in diagnosis of small bowel diseases[J]. LI Xiao-bo GE Zhi-zheng DAI Jun GAO Yun-jie LIU Wen-zhong HU Yun-biao XIAO Shu-dong Department of Gastroenterology,Renji Hospital,Medical College of Shanghai Jiaotong University,Shanghai Institute of Digestive Diseases,Shanghai 200001,China (Li XB Ge ZZ Dai J Gao YJ Liu WZ Hu YB Xiao SD).  Chinese Medical Journal. 2007(01)
[7]Double-balloon enteroscopy in detecting small intestinal bleeding[J]. ZHI Fa-chao, XIAO Bing, JIANG Bo, WAN Tian-mo, GUO Yu, ZHOU Dan, WANG Li-hui, CHEN Jin-feng, XIE Lu, PAN De-shou and ZHOU Dian-yuan Institute of Digestive Medicine, Nanfang Hospital, Southern MedicalUniversity, Guangzhou 510515, China (Zhi FC, Xiao B, Jiang B,Wan TM, Guo Y, Zhou D, Wang LH, Chen JF, Xie L, Pan DSand Zhou DY).  Chinese Medical Journal. 2005(21)



本文編號(hào)：3384809