研究背景小腸是人體消化道最長的器官,由于傳統(tǒng)侵襲性檢查手段的限制,如推進式內鏡（push enteroscopy,PE）只能進入近端小腸對小腸病變進行診治,結腸鏡也只能進入回腸末端進行觀察,因此,既往小腸被認為是消化道檢查的盲區(qū)。既往認為小腸疾�。╯mall bowel diseases, SBDs）發(fā)病率較低,臨床表現(xiàn)非特異,小腸又位于消化道較深的位置,SBDs的診斷和后續(xù)治療常常被延遲,給SBDs患者造成嚴重的經濟負擔和不良的預后,這就使得SBDs的早期識別、診斷和干預在臨床實踐中顯得極為重要。隨著膠囊內鏡（capsule endoscopy, CE）和氣囊輔助內鏡（balloon-assisted enteroscopy, BAE）的臨床應用,使得SBDs得以及時的診斷,同時又可以獲得小腸粘膜的病理學診斷,從而使SBDs診治進入了一個新時代。CE,又稱無線膠囊內鏡（wireless CE）,是本世紀初消化內鏡領域一項重大發(fā)明,最初由以色列Given公司研發(fā)和生產。相對于傳統(tǒng)的非侵襲性小腸檢查如利用放射學檢查的消化道鋇餐、CT, CE能隨自身腸蠕動對腸道粘膜進行觀察,具有非侵襲性、... 

【文章來源】：南方醫(yī)科大學廣東省

【文章頁數(shù)】：129 頁

【學位級別】：博士

【文章目錄】：
摘要
ABSTRACT
第一部分 雙氣囊小腸鏡對可疑小腸疾病診斷價值研究
    引言
    資料與方法
    統(tǒng)計方法
    結果
    結論
    討論
    參考文獻
第二部分 雙氣囊小腸鏡和膠囊內鏡對Meckel憩室診斷價值研究
    引言
    資料和方法
    統(tǒng)計方法
    結果
    結論
    討論
    參考文獻
第三部分 雙氣囊小腸鏡和膠囊內鏡對小腸間葉組織腫瘤診斷價值研究
    引言
    資料與方法
    統(tǒng)計方法
    結果
    討論
    參考文獻
第四部分 膠囊內鏡與CTE/MRI對可疑小腸疾病診斷價值研究：系統(tǒng)回顧與Meta分析
    引言
    資料與方法
    統(tǒng)計方法
    結果
    討論
    參考文獻
全文小結
縮略語英文對照
攻讀博士期間發(fā)表與待發(fā)表研究
致謝
統(tǒng)計學證明


【參考文獻】：
期刊論文
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[2]Double-balloon-enteroscopy-based endoscopic retrograde cholangiopancreatography in post-surgical patients[J]. Martin Raithel,Harald Dormann,Andreas Naegel,Frank Boxberger,Eckhart G Hahn,Markus F Neurath,Juergen Maiss.  World Journal of Gastroenterology. 2011(18)
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