【摘要】：目的觀察腹腔鏡下肝切除術(shù)(LH)聯(lián)合羥基喜樹堿治療肝癌合并肝硬化患者的近期療效。方法選取2013年10月-2015年3月于承德醫(yī)學院附屬醫(yī)院住院治療的肝癌合并肝硬化患者76例,所有患者均先行LH,術(shù)后第4周連續(xù)7 d靜脈滴注4~6 mg羥基喜樹堿予以化療,3周計為1個療程。4個療程后定期隨訪觀察患者黃疸、腹脹等臨床癥狀的改善情況,采用Karnofsky評分法對患者近期生活質(zhì)量進行評價。結(jié)果近期隨訪12個月時,治療有效率為88.16%。臨床癥狀評分及Karnofsky評分顯示,所有患者病情好轉(zhuǎn),臨床癥狀改善,生活質(zhì)量提高,術(shù)后化療毒副反應輕微,均可耐受。結(jié)論 LH聯(lián)合羥基喜樹堿治療肝癌合并肝硬化患者的近期療效好,能夠有效改善患者的臨床癥狀,提升患者的生存質(zhì)量。
[Abstract]:Objective to observe the short-term efficacy of laparoscopic hepatectomy (LH) combined with hydroxycamptothecin in the treatment of liver cancer complicated with liver cirrhosis. Methods from October 2013 to March 2015, 76 patients with liver cancer complicated with liver cirrhosis were enrolled in the affiliated Hospital of Chengde Medical College. All patients were treated with 4 鈮，

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