591例肝硬化患者門靜脈血栓形成的危險因素分析
[Abstract]:Objective to study the risk factors for the prevention of portal vein thrombosis (portal vein thrombosis,PVT) in cirrhotic patients with esophageal and gastric varices rebleeding by endoscopic therapy. Methods retrospective analysis was made on patients with liver cirrhosis who were treated with endoscopy in the Department of Gastroenterology, Zhongshan Hospital affiliated to Fudan University from 2008 to 2013. The clinical data were collected. The factors that may affect the formation of PVT were analyzed by single factor analysis and multi-factor Logistic regression analysis. Results A total of 591 patients were divided into PVT group (n = 122, 20.64%) and non-PVT group (n = 469, 79.36%). Univariate analysis showed that there were significant differences in MELD score, hemoglobin, platelet count, total bilirubin, alanine aminotransferase, blood urea nitrogen and splenectomy ratio between the two groups (P0.05). Multivariate Logistic regression showed that MELD score, decreased blood urea nitrogen, increased D-dimer and history of splenectomy were independent risk factors associated with PVT formation (P = 0.016,0.026,0.014 and 0.001, respectively). Conclusion patients with liver cirrhosis should be followed up regularly on MELD score, liver function, D-dimer level and abdominal ultrasound, and should be more vigilant in patients with history of splenectomy.
【作者單位】: 復旦大學附屬中山醫(yī)院消化科-復旦大學循證醫(yī)學中心;
【基金】:上海市科學技術委員會科研計劃項目(15411950501)~~
【分類號】:R575.2
【相似文獻】
相關期刊論文 前10條
1 段志軍;張煒;李青;;門靜脈血栓的研究進展[J];胃腸病學和肝病學雜志;2010年06期
2 祁興順;韓國宏;王建宏;吳開春;樊代明;;同樣的抗凝,為何不同的開通?——門靜脈血栓程度的臨床意義[J];醫(yī)學爭鳴;2010年05期
3 王雷,潘杰,陳利民,朱麗明;肝硬變門靜脈血栓6例報告[J];浙江預防醫(yī)學;2004年04期
4 梁志會;崔進國;;門靜脈血栓的診斷與介入治療進展[J];中國醫(yī)療器械信息;2008年06期
5 梁志會;崔進國;孫興旺;祝玉芬;于學林;;經導管溶栓治療門靜脈血栓[J];中國醫(yī)療器械信息;2008年06期
6 梁志會;崔進國;孫興旺;祝玉芬;于學林;;門靜脈血栓的介入治療-兩種溶栓途徑的對比研究[J];當代醫(yī)學(中國介入放射學);2008年02期
7 祁興順;韓國宏;樊代明;;經頸靜脈肝內門體分流術治療門靜脈血栓的現(xiàn)狀[J];介入放射學雜志;2010年11期
8 孟祥杰;韓國宏;馮向英;丁杰;吳開春;樊代明;;急性門靜脈血栓經皮途徑的介入治療[J];當代醫(yī)學;2009年17期
9 Pinto R.B. ,Silveira T.R.,Bandinelli E. ,R銉hsig ,李丹;兒童和青少年門靜脈血栓的形成:遺傳性凝血障礙的低發(fā)生率[J];世界核心醫(yī)學期刊文摘(兒科學分冊);2005年02期
10 臧立娜;邢慧慧;王嘉菲;李明娟;劉曉峰;;肝硬化并發(fā)門靜脈血栓研究進展[J];實用肝臟病雜志;2014年04期
相關會議論文 前1條
1 李莉;;門靜脈血栓的診治體會[A];第二屆浙江省消化病學術大會論文匯編[C];2009年
相關重要報紙文章 前1條
1 南雅;治療門靜脈血栓有了新法[N];湖南科技報;2005年
相關碩士學位論文 前3條
1 孟令薇;肝硬化合并門靜脈血栓的臨床特征及相關危險因素分析[D];吉林大學;2016年
2 盛利平;肝硬化失代償門靜脈血栓與凝血功能異常的關系[D];重慶醫(yī)科大學;2016年
3 呂勇;經頸內靜脈肝內門體分流術治療門靜脈血栓伴發(fā)門脈高壓并發(fā)癥的臨床研究[D];第四軍醫(yī)大學;2016年
,本文編號:2465414
本文鏈接:http://sikaile.net/yixuelunwen/xiaohjib/2465414.html