591例肝硬化患者門(mén)靜脈血栓形成的危險(xiǎn)因素分析
[Abstract]:Objective to study the risk factors for the prevention of portal vein thrombosis (portal vein thrombosis,PVT) in cirrhotic patients with esophageal and gastric varices rebleeding by endoscopic therapy. Methods retrospective analysis was made on patients with liver cirrhosis who were treated with endoscopy in the Department of Gastroenterology, Zhongshan Hospital affiliated to Fudan University from 2008 to 2013. The clinical data were collected. The factors that may affect the formation of PVT were analyzed by single factor analysis and multi-factor Logistic regression analysis. Results A total of 591 patients were divided into PVT group (n = 122, 20.64%) and non-PVT group (n = 469, 79.36%). Univariate analysis showed that there were significant differences in MELD score, hemoglobin, platelet count, total bilirubin, alanine aminotransferase, blood urea nitrogen and splenectomy ratio between the two groups (P0.05). Multivariate Logistic regression showed that MELD score, decreased blood urea nitrogen, increased D-dimer and history of splenectomy were independent risk factors associated with PVT formation (P = 0.016,0.026,0.014 and 0.001, respectively). Conclusion patients with liver cirrhosis should be followed up regularly on MELD score, liver function, D-dimer level and abdominal ultrasound, and should be more vigilant in patients with history of splenectomy.
【作者單位】: 復(fù)旦大學(xué)附屬中山醫(yī)院消化科-復(fù)旦大學(xué)循證醫(yī)學(xué)中心;
【基金】:上海市科學(xué)技術(shù)委員會(huì)科研計(jì)劃項(xiàng)目(15411950501)~~
【分類號(hào)】:R575.2
【相似文獻(xiàn)】
相關(guān)期刊論文 前10條
1 段志軍;張煒;李青;;門(mén)靜脈血栓的研究進(jìn)展[J];胃腸病學(xué)和肝病學(xué)雜志;2010年06期
2 祁興順;韓國(guó)宏;王建宏;吳開(kāi)春;樊代明;;同樣的抗凝,為何不同的開(kāi)通?——門(mén)靜脈血栓程度的臨床意義[J];醫(yī)學(xué)爭(zhēng)鳴;2010年05期
3 王雷,潘杰,陳利民,朱麗明;肝硬變門(mén)靜脈血栓6例報(bào)告[J];浙江預(yù)防醫(yī)學(xué);2004年04期
4 梁志會(huì);崔進(jìn)國(guó);;門(mén)靜脈血栓的診斷與介入治療進(jìn)展[J];中國(guó)醫(yī)療器械信息;2008年06期
5 梁志會(huì);崔進(jìn)國(guó);孫興旺;祝玉芬;于學(xué)林;;經(jīng)導(dǎo)管溶栓治療門(mén)靜脈血栓[J];中國(guó)醫(yī)療器械信息;2008年06期
6 梁志會(huì);崔進(jìn)國(guó);孫興旺;祝玉芬;于學(xué)林;;門(mén)靜脈血栓的介入治療-兩種溶栓途徑的對(duì)比研究[J];當(dāng)代醫(yī)學(xué)(中國(guó)介入放射學(xué));2008年02期
7 祁興順;韓國(guó)宏;樊代明;;經(jīng)頸靜脈肝內(nèi)門(mén)體分流術(shù)治療門(mén)靜脈血栓的現(xiàn)狀[J];介入放射學(xué)雜志;2010年11期
8 孟祥杰;韓國(guó)宏;馮向英;丁杰;吳開(kāi)春;樊代明;;急性門(mén)靜脈血栓經(jīng)皮途徑的介入治療[J];當(dāng)代醫(yī)學(xué);2009年17期
9 Pinto R.B. ,Silveira T.R.,Bandinelli E. ,R銉hsig ,李丹;兒童和青少年門(mén)靜脈血栓的形成:遺傳性凝血障礙的低發(fā)生率[J];世界核心醫(yī)學(xué)期刊文摘(兒科學(xué)分冊(cè));2005年02期
10 臧立娜;邢慧慧;王嘉菲;李明娟;劉曉峰;;肝硬化并發(fā)門(mén)靜脈血栓研究進(jìn)展[J];實(shí)用肝臟病雜志;2014年04期
相關(guān)會(huì)議論文 前1條
1 李莉;;門(mén)靜脈血栓的診治體會(huì)[A];第二屆浙江省消化病學(xué)術(shù)大會(huì)論文匯編[C];2009年
相關(guān)重要報(bào)紙文章 前1條
1 南雅;治療門(mén)靜脈血栓有了新法[N];湖南科技報(bào);2005年
相關(guān)碩士學(xué)位論文 前3條
1 孟令薇;肝硬化合并門(mén)靜脈血栓的臨床特征及相關(guān)危險(xiǎn)因素分析[D];吉林大學(xué);2016年
2 盛利平;肝硬化失代償門(mén)靜脈血栓與凝血功能異常的關(guān)系[D];重慶醫(yī)科大學(xué);2016年
3 呂勇;經(jīng)頸內(nèi)靜脈肝內(nèi)門(mén)體分流術(shù)治療門(mén)靜脈血栓伴發(fā)門(mén)脈高壓并發(fā)癥的臨床研究[D];第四軍醫(yī)大學(xué);2016年
,本文編號(hào):2465414
本文鏈接:http://sikaile.net/yixuelunwen/xiaohjib/2465414.html