【摘要】：目的：腸易激綜合征(Irritable Bowel Syndrome，IBS)是世界范圍的常見慢性功能性疾病。隨著生活水平的提高和飲食方式的改變，其發(fā)病率在國內(nèi)外都有逐年升高的趨勢(shì)。功能性胃腸病必須是在排除器質(zhì)性疾病基礎(chǔ)上診斷的消化道疾病，有別于腫瘤、炎癥等顯著器質(zhì)性病變。功能性胃腸病病程長，病情復(fù)雜，多數(shù)遷延起伏，不易治愈，顯著影響患者的生活質(zhì)量，使其反復(fù)多方求醫(yī)造成醫(yī)療花費(fèi)巨大和醫(yī)療資源浪費(fèi)。患者不僅長期承受軀體不適，而且極易同時(shí)伴有心理疾病。本研究是應(yīng)用羅馬III標(biāo)準(zhǔn)進(jìn)行石河子大學(xué)不同專業(yè)碩士研究生腸易激綜合征的流行病學(xué)和相關(guān)影響因素的課題研究。探討石河子大學(xué)不同專業(yè)（文學(xué)、醫(yī)學(xué)、理學(xué)）碩士研究生之間IBS發(fā)病率、影響因素的差異，為進(jìn)一步探討高學(xué)歷人才IBS的發(fā)病及其與生活相關(guān)因素、精神心理因素的關(guān)系提供理論基礎(chǔ)，為臨床預(yù)防及治療IBS提供參考。 方法：對(duì)石河子大學(xué)不同專業(yè)（醫(yī)學(xué)、文學(xué)、理學(xué)）1000名在校碩士研究生進(jìn)行問卷調(diào)查，包括根據(jù)腸易激綜合征羅馬III診斷標(biāo)準(zhǔn)設(shè)計(jì)本研究所采用的問卷查表、ZUNG焦慮自評(píng)量表(self-rating anxiety scale, SAS)、ZUNG抑郁自評(píng)量表(self-rating depressionscale, SDS)、IBS生活因素調(diào)查表。調(diào)查時(shí)間自2012年12月至2013年6月，并對(duì)結(jié)果進(jìn)行統(tǒng)計(jì)和分析。 結(jié)果：1000份調(diào)查問卷共獲得有效調(diào)查問卷915份，總體有效率為91.5%。被診斷為IBS的為83人，IBS總體患病率為9.07%，其中男性40人，患病率為8.32%，女性43人，患病率為9.91%。醫(yī)學(xué)專業(yè)患病率為8.97%，，文學(xué)專業(yè)患病率為8.36%，理學(xué)專業(yè)患病率為9.81%。女性患病率高于男性（9.91%vs.8.32%，χ2=4.312，P=0.037）；醫(yī)學(xué)專業(yè)與理學(xué)專業(yè)以及文學(xué)專業(yè)之間IBS的患病率沒有明顯的統(tǒng)計(jì)學(xué)差異；logistic回歸分析示，進(jìn)食生冷食物頻率≥3次每周、進(jìn)食乳制品頻率≥3次每周、進(jìn)食高纖維食物頻率＜4次每周、體育活動(dòng)時(shí)間頻率＜4小時(shí)每周、失眠次數(shù)≥3次每周、焦慮、抑郁可能是IBS患病的危險(xiǎn)因素。 結(jié)論：不同專業(yè)碩士研究生之間IBS患病率無明顯差異，女性患病率高于男性，進(jìn)食生冷食物、進(jìn)食乳制品頻率≥3次每周、進(jìn)食高纖維食物頻率＜4次每周、體育活動(dòng)時(shí)間＜4小時(shí)每周、失眠次數(shù)≥3次每周，以及處于焦慮、抑郁狀態(tài)均與IBS的發(fā)病有關(guān)，或與上述因素共同作用有關(guān)，應(yīng)予以針對(duì)性的干預(yù)措施做好防治工作。
[Abstract]:Objective: irritable bowel syndrome (Irritable Bowel Syndrome,IBS) is a common chronic functional disease worldwide. With the improvement of living standard and the change of dietary style, the incidence of disease has been increasing year by year at home and abroad. Functional gastrointestinal disease must be diagnosed on the basis of excluding organic diseases, which is different from tumor, inflammation and other significant organic diseases. The course of functional gastrointestinal disease is long, the disease is complex, most of them are undulating and difficult to cure, which significantly affect the quality of life of the patients, and make them spend a lot of medical treatment and waste medical resources. Patients not only suffer from long-term physical discomfort, but also easily accompanied by psychological illness. This study is to study the epidemiology and related influencing factors of irritable bowel syndrome (IBS) in graduate students of different specialties in Shihezi University using III standard in Rome. To explore the incidence and influencing factors of IBS among graduate students of different majors (literature, medicine, science) in Shihezi University, in order to further explore the incidence of IBS and its related factors with life. The relationship between mental and psychological factors provides a theoretical basis for clinical prevention and treatment of IBS. Methods: a questionnaire survey was conducted among 1000 graduate students of different specialties (medicine, literature, science) in Shihezi University. The questionnaire was designed according to Roman III diagnostic criteria for irritable bowel syndrome (IBS). ZUNG self-rating anxiety scale (self-rating anxiety scale, SAS), ZUNG self-rating Depression scale) (self-rating depressionscale, SDS), IBS Life Factor questionnaire). The survey was conducted from December 2012 to June 2013 and the results were statistically analyzed. Results: a total of 915 effective questionnaires were obtained from 1000 questionnaires, and the overall effective rate was 91.5%. The total prevalence rate of IBS was 9.07. The prevalence rate was 8.32 in 40 males and 43 in females, and the prevalence rate was 9.91%. The prevalence rate of medicine, literature and science was 8.97, 8.36 and 9.81 respectively. The prevalence rate of IBS in women was higher than that in men (9.91 vs 8.32, 蠂 2 = 4.312), and there was no significant difference in the prevalence of IBS between the major of medicine and science and the major of literature. Logistic regression analysis showed that the frequency of eating raw and cold food was more than 3 times a week, the frequency of consuming dairy products was more than 3 times per week, the frequency of consuming high fiber food was less than 4 times a week, the frequency of physical activity was less than 4 hours per week, the frequency of insomnia was more than 3 times per week, anxiety. Depression may be a risk factor for IBS. Conclusion: there was no significant difference in the prevalence of IBS among postgraduates of different specialties. The prevalence of IBS in females was higher than that in males. The frequency of dairy products was more than 3 times a week, and the frequency of high fiber foods was less than 4 times per week. Physical activity time < 4 hours per week, insomnia times 鈮

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