【摘要】：本研究將82例胃潰瘍患者根據(jù)隨機(jī)數(shù)字表分為兩組。予以對(duì)照組鹽酸雷尼替丁治療,予以觀察組奧美拉唑治療。對(duì)比兩組治療前后的療效及患者IL-2、IL-6、CRP、TNF-α、SOD、VEGF、EGF的水平變化之后,結(jié)果發(fā)現(xiàn)觀察組有效率明顯高于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(p0.05);兩組治療前的IL-2、IL-6、CRP水平差異無(wú)統(tǒng)計(jì)學(xué)意義(p0.05);治療后的IL-6、CRP水平較治療前降低,IL-2水平較治療前升高,且觀察組較對(duì)照組變化明顯(p0.05);兩組治療前的TNF-α、SOD、VEGF、EGF水平差異無(wú)統(tǒng)計(jì)學(xué)意義(p0.05);治療后的TNF-α水平較治療前降低,SOD、VEGF、EGF水平較治療前高,且觀察組比對(duì)照組的變化明顯(p0.05)。提示奧美拉唑在治療胃潰瘍方面效果顯著,可改善炎癥反應(yīng),快速修復(fù)潰瘍面,是治療胃潰瘍的有效藥物。
[Abstract]:82 patients with gastric ulcer were randomly divided into two groups. The control group was treated with ranitidine hydrochloride and the observation group with omeprazole. After comparing the curative effect before and after treatment and the changes of IL-2,IL-6,CRP,TNF- 偽 and SOD,VEGF,EGF levels in the two groups, the results showed that the effective rate in the observation group was significantly higher than that in the control group. The difference was statistically significant (p0. 05), there was no significant difference in IL-2,IL-6,CRP level between the two groups before treatment (p0. 05), the IL-6,CRP level after treatment was lower than that before treatment, and the IL-2 level was higher than that before treatment. The levels of TNF- 偽 and SOD,VEGF,EGF in the observation group were significantly higher than those in the control group (p0.05), the levels of TNF- 偽 and SOD,VEGF,EGF in the observation group were significantly higher than those in the control group (p0.05), and the levels of TNF- 偽 in the observation group were significantly higher than those in the control group (p0.05). It is suggested that omeprazole is an effective drug for the treatment of gastric ulcer.
【作者單位】： 延安大學(xué)西安創(chuàng)新學(xué)院;
【基金】：延安大學(xué)西安創(chuàng)新學(xué)院提供項(xiàng)目資助
【分類號(hào)】：R573.1

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