【摘要】：目的:了解體檢人群的上消化道疾病情況,探討體檢人群行胃鏡檢查的必要性,提高人們行胃鏡檢查的意識(shí),同時(shí)為提高早癌檢出率提供臨床依據(jù)。方法:通過(guò)對(duì)太鋼集團(tuán)18613名職工進(jìn)行問(wèn)卷調(diào)查,入選可行胃鏡檢查者9885例,對(duì)其電話通知并于太鋼總醫(yī)院行胃鏡體檢者4647例,體檢者均無(wú)禁忌癥,自愿簽署胃鏡檢查知情同意書(shū)后行胃鏡檢查,最后對(duì)2014年1月-2016年12月于太鋼總醫(yī)院內(nèi)鏡中心行胃鏡體檢的4647例太鋼集團(tuán)職工的胃鏡結(jié)果進(jìn)行回顧性分析,統(tǒng)計(jì)其性別、年齡、疾病檢出率的相關(guān)性。結(jié)果:4647例受檢者中,年齡最小為27歲,最大為74歲,平均年齡為47.48±5.82歲,女性873例(18.8%),男性3774例(81.2%),青年組(39歲以下)801例(17.2%),中年組(40-59歲)3717例(80.0%),老年組(60歲以上)129例(2.8%);其中反流性食管炎465例(10.0%),Barrett食管84例(1.8%),慢性非萎縮性胃炎3531例(72.0%),慢性萎縮性胃炎243例(5.2%),消化性潰瘍673例(14.5%),胃息肉498例(10.7%),上消化道癌癥44例(0.9%)。4647例受檢者中,Barrett食管和上消化道癌癥檢出率男女比較無(wú)統(tǒng)計(jì)學(xué)意義(P0.05);反流性食管炎、慢性非萎縮性胃炎、慢性萎縮性胃炎、消化性潰瘍、胃息肉檢出率男女比較有統(tǒng)計(jì)學(xué)意(P0.05),反流性食管炎、慢性萎縮性胃炎、消化性潰瘍男性高于女性,慢性非萎縮性胃炎、胃息肉檢出率女性比男性多。4647例受檢者中,不同年齡組Barrett食管、消化性潰瘍檢出率無(wú)統(tǒng)計(jì)學(xué)意義(P0.05);不同年齡組反流性食管炎、慢性非萎縮性胃炎、慢性萎縮性胃炎、胃息肉、上消化道癌癥檢出率有統(tǒng)計(jì)學(xué)意義(P0.05),且反流性食管炎、慢性萎縮性胃炎、上消化道癌癥以40歲以上人群發(fā)病為主,慢性非萎縮性胃炎、胃息肉以60歲以上多發(fā)。上消化道癌癥41例(0.9%),早癌8例(19.5%),進(jìn)展期癌33例(80.5%),主要以進(jìn)展期癌檢出為主,早癌在不同性別組和不同年齡組中的檢出率均無(wú)統(tǒng)計(jì)學(xué)意義(P0.05),但早癌在40歲以上人群中有檢出率。結(jié)論:體檢人群行胃鏡檢查結(jié)果中,不同的上消化道疾病在40歲以上人群中有較高的檢出率,但男女之間差異不一;此外,上消化道早癌在40歲以上人群中也有一定的檢出率。因此,40歲以上人群應(yīng)注意胃鏡體檢,提高疾病檢出率,降低癌變率。
[Abstract]:Objective: to understand the condition of upper digestive tract diseases in people with physical examination, to explore the necessity of gastroscopy, to improve people's consciousness of gastroscopy, and to provide clinical basis for improving the detection rate of early cancer. Methods: a questionnaire survey was conducted among 18613 workers of Taigang Group. 9885 cases were selected for feasible gastroscopy examination. 4647 cases were informed by telephone and examined by gastroscope in the General Hospital of Taiyuan Iron and Steel Group. There was no contraindication in all the patients. The results of gastroscopy were analyzed retrospectively in 4647 workers of Taigang Group from January 2014 to December 2016 at the endoscopic center of Taiyuan Iron and Steel General Hospital, and the results of gastroscopy were analyzed retrospectively, and their gender and age were counted. Correlation of disease detection rate. Results among the 4647 subjects, the youngest was 27 years old, the oldest was 74 years old, the average age was 47.48 鹵5.82 years old. 873 female (18.8%), male 3774 (81.2%), young group (under 39) 801 cases (17.2%), middle-aged group (40-59 years old) 3717 cases (80.0%), senile group (over 60 years old) 129 cases (2.8%), reflux esophagitis 465 cases (10.0%) Barrett's esophagus 84 cases (1.8%), chronic atrophic gastritis 3531 cases (72.0%), chronic atrophic gastritis 3531 cases (72.0%) There were 243 cases of gastritis (5.2%), 673 cases of peptic ulcer (14.5%), 498 cases of gastric polyp (10.7%), 44 cases of upper digestive tract cancer (0.9%). The detection rate of chronic non-atrophic gastritis, chronic atrophic gastritis, peptic ulcer, gastric polyp was statistically significant (P0.05), reflux esophagitis, chronic atrophic gastritis, peptic ulcer male than female, chronic non-atrophic gastritis, chronic non-atrophic gastritis, The detection rate of gastric polyps in women was higher than that in men. There was no significant difference in the detection rate of peptic ulcer and Barrett esophagus in different age groups (P0.05), and the detection rate of reflux esophagitis, chronic non-atrophic gastritis, chronic atrophic gastritis, gastric polyp in different age groups was not significant. The detection rate of upper gastrointestinal cancer was statistically significant (P0.05), and reflux esophagitis, chronic atrophic gastritis, upper digestive tract cancer in the population over 40 years old, chronic non-atrophic gastritis, gastric polyps more than 60 years old. 41 cases of upper gastrointestinal cancer (0.9%), 8 cases of early cancer (19.5%), 33 cases of advanced carcinoma (80.5%), mainly advanced cancer, the detection rate of early cancer in different sex group and different age group was not statistically significant (P0.05), but early cancer was detected in people over 40 years old. Conclusion: the results of gastroscopy showed that the detection rate of upper digestive tract diseases was higher in people over 40 years old, but the difference was different between men and women, in addition, the detection rate of early upper digestive tract cancer was also found in people over 40 years old. Therefore, people over 40 years old should pay attention to gastroscopy examination to improve the detection rate of diseases and reduce the canceration rate.
【學(xué)位授予單位】：山西醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R573

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