【摘要】：目的:探討肝癌并發(fā)癥上消化道出血患者的肝臟硬度與肝纖維化的變化情況與相關性。方法:2010年9月至2014年2月選擇在我院進行檢查的肝癌患者80例,其中無并發(fā)上消化道出血48例(A組),并發(fā)上消化道出血32例(B組),兩組進行血生化常規(guī)、肝臟硬度與肝纖維化的檢測,并且進行相關性分析。結果:B組患者的血小板、丙氨酸氨基轉移酶、甲胎蛋白值都明顯高于A組,而白蛋白值明顯低于A組(均P0.05)。A組患者的肝臟硬度為(10.42±4.12)k Pa,而B組為(15.21±4.68)k Pa,B組的肝臟硬度明顯高于A組(P0.05)。B組患者的血清HA、LN、C-Ⅳ和PⅢP含量都明顯高于A組(P0.05)。Spearman相關分析表明肝臟硬度與血清HA、LN、C-Ⅳ和PⅢP含量都呈明顯正向相關性(P0.05)。結論:肝癌并發(fā)癥上消化道出血患者的肝臟硬度檢測能反映血清肝纖維化水平,兩者之間具有正向相關性,肝臟硬度可用于肝癌并發(fā)癥上消化道出血患者的非創(chuàng)傷性診斷,值得臨床推廣應用。
[Abstract]:Objective: to investigate the relationship between liver hardness and hepatic fibrosis in patients with upper gastrointestinal hemorrhage. Methods: from September 2010 to February 2014, 80 patients with liver cancer were selected for examination in our hospital, including 48 patients without upper gastrointestinal bleeding (group A) and 32 patients with upper gastrointestinal bleeding (group B). The relationship between liver hardness and liver fibrosis was analyzed. Results the levels of platelet, alanine aminotransferase and alpha-fetoprotein in group B were significantly higher than those in group A. However, albumin level was significantly lower than that in group A (P0.05). The liver hardness in group A was (10.42 鹵4.12) k Pa, while that in group B was (15.21 鹵4.68) kPA. The hardness of liver in group B was significantly higher than that in group A (P0.05) .B and P 鈪，

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