本文選題：非酒精性脂肪肝病 + BARD評分　； 參考：《中國現(xiàn)代醫(yī)學(xué)雜志》2017年22期

【摘要】：目的評價(jià)天冬氨酸氨基轉(zhuǎn)移酶血小板比率指數(shù)(APRI)、BARD(BMI,AST/ALT,DM)評分、BAAT(BMI,年齡,ALT,TG)評分和非酒精性脂肪肝病(NAFLD)纖維化評分(NFS)4種肝纖維化評分系統(tǒng)在該院NAFLD患者中的臨床應(yīng)用價(jià)值,并探索聯(lián)合使用評分系統(tǒng)的應(yīng)用效能。方法選取2013年7月~2016年9月確診為NAFLD的患者為研究對象。測定其臨床及實(shí)驗(yàn)室指標(biāo),計(jì)算NFS、APRI、BARD、BAAT得分,并以組織學(xué)結(jié)果為參照,評價(jià)這些系統(tǒng)的診斷價(jià)值。結(jié)果 96例NAFLD患者中66例有肝纖維化。經(jīng)計(jì)算,NFS系統(tǒng)診斷NAFLD患者是否有肝纖維化的敏感性為1.92%,特異性為100%;APRI系統(tǒng)的敏感性為7.58%,特異性為93.33%;BARD系統(tǒng)的敏感性為63.64%,特異性為16.67%;BAAT系統(tǒng)的敏感性為0,特異性為94.74%。NFS聯(lián)合APRI的敏感性為10.71%,特異性為90%;BARD聯(lián)合BAAT的敏感性為76.36%,特異性為10.34%。結(jié)論當(dāng)聯(lián)合使用BARD和BAAT時(shí),可獲得高敏感性,故可用于NAFLD的初步篩查;當(dāng)單獨(dú)使用NFS或APRI時(shí),其特異性較高,可用于NAFLD的進(jìn)一步鑒別診斷。
[Abstract]:Objective to evaluate the clinical application value of aspartate aminotransferase platelet ratio index (APRI) BARD (BMIAST / alt DM) score BAAT (BMIs) and nonalcoholic fatty liver disease (NAFLD) fibrosis scoring system (NFS) in patients with NAFLD in our hospital. And explore the application efficiency of the joint use scoring system. Methods patients diagnosed with NAFLD from July 2013 to September 2016 were selected as study subjects. The clinical and laboratory indexes were measured, and the BAAT scores were calculated. The diagnostic value of these systems was evaluated according to the histological results. Results 66 of 96 NAFLD patients had hepatic fibrosis. The sensitivity of the NFS system in diagnosing hepatic fibrosis in NAFLD patients was 1.922.The specificity of APRI system was 7.58, the specificity was 93.330.The sensitivity of Bard system was 63.64. The sensitivity of BAAT system was 0, and the specificity was 94.74.NFS. The sensitivity of APRI was 10.71, the specificity was 90% and the sensitivity of BAAT was 76.36 and the specificity was 10.34. Conclusion the combination of Bard and BAAT can obtain high sensitivity, so it can be used in the preliminary screening of NAFLD, and the specificity of NAFLD is higher when using NFS or APRI alone, which can be used for further differential diagnosis of NAFLD.
【作者單位】： 鄭州人民醫(yī)院消化科;新鄉(xiāng)醫(yī)學(xué)院第一附屬醫(yī)院消化科;
【分類號】：R575
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本文編號：2106398