本文選題：脂肪肝 + 聲速匹配技術(shù)��； 參考：《實(shí)用醫(yī)學(xué)雜志》2015年24期

【摘要】：目的:通過(guò)測(cè)量不同程度脂肪肝患者肝組織的聲速值,為脂肪肝的診斷提供量化依據(jù),并初步探討脂肪肝分度的臨界值。方法:應(yīng)用聲速匹配技術(shù)測(cè)量140例受試者(輕、中、重度脂肪肝各31、38、33例,健康自愿者38例)肝組織區(qū)域速度指數(shù)(ZSI),計(jì)算聲速值,分析不同程度脂肪肝患者肝組織的聲速值變化,并構(gòu)建差異有統(tǒng)計(jì)學(xué)意義的不同組別間的ROC曲線。結(jié)果:脂肪肝患者的聲速值隨著脂肪肝程度的加重而降低,差異有統(tǒng)計(jì)學(xué)意義(P0.05);正常對(duì)照組與輕度脂肪肝組、輕度脂肪肝組與中度脂肪肝組差異有統(tǒng)計(jì)學(xué)意義,中度脂肪肝組與重度脂肪肝組差異無(wú)統(tǒng)計(jì)學(xué)意義;正常對(duì)照組與輕度脂肪肝組、輕度脂肪肝組與中重度脂肪肝組臨界聲速值分別為1 545 m/s、1 505 m/s,ROC曲線下面積分別為0.96、0.93,約登指數(shù)分別為0.86、0.78,靈敏度分別為89.5%、93.5%,特異度分別為96.8%、84.5%。結(jié)論:肝組織聲速值隨著脂肪肝程度的加重而降低,聲速匹配技術(shù)能夠?yàn)橹靖蔚姆侄忍峁┝炕罁?jù)。
[Abstract]:Objective: to provide a quantitative basis for the diagnosis of fatty liver by measuring the sonic velocity of liver tissue in patients with fatty liver of different degrees, and to explore the critical value of fatty liver grading. Methods: the regional velocity index (ZSI) of liver tissue was measured in 140 patients with mild, moderate and severe fatty liver (31 ~ 833 mild, moderate and severe fatty liver, 38 healthy volunteers) by using sound velocity matching technique. The velocity of sound was calculated and the changes of sound velocity in liver tissue of patients with different degrees of fatty liver were analyzed. The ROC curves of different groups with statistical significance were constructed. Results: the sonic velocity of fatty liver patients decreased with the severity of fatty liver, the difference was statistically significant (P0.05), the difference between normal control group and mild fatty liver group, mild fatty liver group and moderate fatty liver group was statistically significant. There was no significant difference between moderate fatty liver group and severe fatty liver group. The critical sonic velocity values of mild fatty liver group and moderate severe fatty liver group were 1 545 m / s ~ (-1) ~ 1 505 m / s ~ (-1) ROC curve, respectively, respectively. The area of ROC curve was 0.966 鹵0.93, the Yorden index was 0.86 ~ 0.78, the sensitivity was 89. 5% and the specificity was 96. 8% and 84. 5%, respectively. Conclusion: the sonic velocity of liver tissue decreases with the aggravation of fatty liver, and the technique of ultrasonic velocity matching can provide quantitative basis for the grading of fatty liver.
【作者單位】： 華北理工大學(xué)附屬醫(yī)院;
【基金】：河北省科技計(jì)劃基金資助項(xiàng)目(編號(hào):132777196)
【分類號(hào)】：R575.5

【相似文獻(xiàn)】

相關(guān)會(huì)議論文 前1條

1 杜恒;劉東權(quán);;超聲系統(tǒng)聲速優(yōu)化模擬與算法[A];中國(guó)生物醫(yī)學(xué)工程進(jìn)展——2007中國(guó)生物醫(yī)學(xué)工程聯(lián)合學(xué)術(shù)年會(huì)論文集（上冊(cè)）[C];2007年

相關(guān)碩士學(xué)位論文 前1條

1 楊美霞;疏松鐵沖擊卸載聲速與鐵的高壓熔化線研究[D];西南交通大學(xué);2005年

，

本文編號(hào)：2075549