本文選題：細(xì)菌性肝膿腫 + 致病菌�。� 參考：《西部醫(yī)學(xué)》2017年05期

【摘要】：目的探討細(xì)菌性肝膿腫的病原菌分布,為臨床經(jīng)驗(yàn)性選擇抗菌藥物提供依據(jù)。方法回顧性分析重慶醫(yī)科大學(xué)附屬第一醫(yī)院于2013年1月~2015年12月收治的68例細(xì)菌性肝膿腫患者主要臨床表現(xiàn)、基礎(chǔ)疾病、降鈣素原檢查結(jié)果、病原學(xué)檢查細(xì)菌分布及藥敏試驗(yàn)結(jié)果、臨床治療方案選擇。結(jié)果膿液和血標(biāo)本中共分離培養(yǎng)出94株細(xì)菌,其中革蘭陰性菌78株,以肺炎克雷伯桿菌(57株)為主,其次為大腸埃希菌(15株);革蘭陽(yáng)性菌16株,主要為星座鏈球菌(4株),咽峽炎鏈球菌、中間鏈球菌、溶血葡萄球菌、屎腸球菌(D群)各2株。藥敏試驗(yàn)結(jié)果顯示針對(duì)革蘭陰性菌厄他培南、亞胺培南西司他丁、替加環(huán)素、頭孢替坦、頭孢吡肟、頭孢他啶、頭孢西丁、阿米卡星、哌拉西林他唑巴坦敏感度均90%;對(duì)于革蘭陽(yáng)性菌,替加環(huán)素、萬(wàn)古霉素、奎努普汀/達(dá)福普汀敏感度90%。對(duì)于伴隨疾病,肺炎克雷伯桿菌肝膿腫好發(fā)于糖尿病患者,而非肺炎克雷伯菌肝膿腫好發(fā)于存在膽道疾病基礎(chǔ)的患者。結(jié)論細(xì)菌性肝膿腫致病菌主要為肺炎克雷伯桿菌,好發(fā)于糖尿病患者,其對(duì)喹諾酮類、氨基糖苷類、β-內(nèi)酰胺類、碳青霉烯類抗菌藥物敏感度較高。
[Abstract]:Objective to investigate the distribution of pathogenic bacteria of bacterial liver abscess in order to provide the basis for clinical empirical selection of antibiotics. Methods the main clinical manifestations, basic diseases, calcitonin test results and pathogenic bacteria examination of 68 patients with bacterial liver abscess treated in First Affiliated Hospital of Chongqing Medical University in January 2013, ~2015, in December, were analyzed retrospectively. Results 94 strains of bacteria were isolated and cultured in pus and blood samples, including 78 Gram-negative bacteria, 57 strains of Klebsiella pneumoniae (57 strains), followed by Escherichia coli (15), and 16 Gram-positive bacteria (4 strains), Streptococcus angina, Streptococcus intermedius, dissolution. 2 strains of Staphylococcus aureus and Enterococcus faecium (group D). The results of drug sensitivity test showed that the gram-negative bacilli, imipenem, tigatin, ceftiettan, cefimoxime, ceftazidime, cefoxitin, cefoxitin, Amikacin, piperacillin and tazobactam were sensitive to 90%, and Gram-positive bacteria, tetracycline, vancomycin, Kui Nu 90%. sensitivity 90%. for the associated disease, Klebsiella pneumoniae liver abscess in diabetic patients, and not Klebsiella pneumoniae liver abscess in the base of the existence of biliary disease. Conclusion bacterial liver abscess is mainly caused by Klebsiella pneumoniae, good hair in diabetic patients, quinolones, amino sugar Glucosides, beta lactam, carbapenem antibiotics are highly sensitive.
【作者單位】： 重慶醫(yī)科大學(xué)附屬第一醫(yī)院感染科·重慶市傳染病寄生蟲(chóng)病學(xué)重點(diǎn)實(shí)驗(yàn)室;
【基金】：人事部科研基金(09958013) 重慶市自然科學(xué)基金(CSTC2009BB5061)
【分類號(hào)】：R575.4

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【共引文獻(xiàn)】

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1 張婷婷;袁U，

本文編號(hào)：2027287