脂肪肝相關(guān)危險(xiǎn)因素的評(píng)估
本文選題:脂肪肝 + 危險(xiǎn)因素; 參考:《福建醫(yī)科大學(xué)》2014年碩士論文
【摘要】:目的 探討脂肪肝發(fā)病的相關(guān)危險(xiǎn)因素。 方法 選取2013.9-11月具有完整資料的福建省立醫(yī)院體檢中心的健康體檢者1000例,排除惡性腫瘤、病毒性肝炎標(biāo)志物陽(yáng)性、慢性胰腺炎、嚴(yán)重腎功損傷、急性感染或創(chuàng)傷、長(zhǎng)期激素應(yīng)用史,通過(guò)問(wèn)卷調(diào)查、體格檢查、實(shí)驗(yàn)室檢測(cè)及腹部超聲檢查對(duì)脂肪肝組的年齡、性別、體重指數(shù)、血壓、血糖、血脂、血尿酸、肝功能、血常規(guī)及有無(wú)膽石癥與非脂肪肝組進(jìn)行對(duì)比分析。 結(jié)果 1000例體檢者中,,超聲診斷出脂肪肝416例(41.6%),其中男性287例(51.9%),女性129例(28.9%),二者檢出率間差異有統(tǒng)計(jì)學(xué)意義(χ=54.011,P0.05);脂肪肝組超重、肥胖、糖代謝紊亂、高血壓、血脂異常、高尿酸血癥的患病率高于非脂肪肝組,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。單因素分析顯示,脂肪肝組體重指數(shù)、收縮壓、舒張壓、甘油三酯、總膽固醇、低密度脂蛋白、空腹血糖、尿酸等均高于非脂肪肝組,差異有統(tǒng)計(jì)學(xué)意義(P0.05),而高密度脂蛋白膽固醇則低于非脂肪肝組,差異亦有統(tǒng)計(jì)學(xué)意義(P0.05)。多因素Logistic回歸結(jié)果顯示年齡、性別(男性)、體重指數(shù)、甘油三酯、低密度脂蛋白、空腹血糖6項(xiàng)指標(biāo)進(jìn)入了回歸方程(P0.05)。 結(jié)論 超重、肥胖、高血壓、糖代謝紊亂、血脂異常、高尿酸血癥都增加了脂肪肝的患病風(fēng)險(xiǎn)。年齡、性別、體重指數(shù)、甘油三酯、低密度脂蛋白、空腹血糖是脂肪肝發(fā)病的危險(xiǎn)因素。
[Abstract]:Objective to investigate the risk factors of fatty liver disease. Methods 1000 healthy persons from Fujian Provincial Hospital physical examination Center from September to November 2013.were selected to exclude malignant tumor, positive markers of viral hepatitis and chronic pancreatitis. Severe renal injury, acute infection or trauma, long history of hormone use, age, sex, body mass index, blood pressure, blood glucose, blood lipid, serum uric acid in fatty liver group by questionnaire, physical examination, laboratory and abdominal ultrasound, The liver function, blood routine, cholelithiasis and non-fatty liver were compared and analyzed. There were 41.6 cases of fatty liver diagnosed by ultrasound, of which 287 cases were male (51.9%), 129 cases were female (28.9%), the difference between them was statistically significant (蠂 ~ (2 +) 54.011) (P 0.05), fatty liver group was overweight, obesity, disorder of glucose metabolism, hypertension, abnormal blood lipid. The prevalence of hyperuricemia was higher than that of non-fatty liver (P 0.05). Univariate analysis showed that body mass index, systolic blood pressure, diastolic blood pressure, triglyceride, total cholesterol, low density lipoprotein, fasting blood glucose and uric acid in fatty liver group were higher than those in non-fatty liver group. The difference was statistically significant (P 0.05), and high density lipoprotein cholesterol (HDL-C) was significantly lower than that in non fatty liver group (P 0.05). The results of multivariate logistic regression showed that age, sex (male, body mass index, triglyceride, low density lipoprotein, fasting blood glucose) entered the regression equation (P 0.05). Conclusion overweight, obesity, hypertension, disorder of glucose metabolism, dyslipidemia, and hyperlipidemia were found in the regression equation. Hyperuricemia increases the risk of fatty liver disease. Age, sex, body mass index, triglyceride, low density lipoprotein, fasting blood glucose are risk factors for fatty liver.
【學(xué)位授予單位】:福建醫(yī)科大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2014
【分類號(hào)】:R575.5
【參考文獻(xiàn)】
相關(guān)期刊論文 前10條
1 李俊峰;湯紹輝;楊冬華;楊見(jiàn)權(quán);;非酒精性脂肪肝與膽石癥的關(guān)系[J];廣東醫(yī)學(xué);2006年07期
2 鄒強(qiáng),孫西河,王濱,謝海柱;脂肪肝MR定量診斷的實(shí)驗(yàn)研究[J];中國(guó)臨床醫(yī)學(xué)影像雜志;2001年03期
3 洪傳美;;B超在脂肪肝診斷中的應(yīng)用研究[J];現(xiàn)代實(shí)用醫(yī)學(xué);2010年02期
4 閆蓉;牛春燕;田宇;焦述江;馬惠霞;;烏魯木齊地區(qū)漢族成人脂肪肝及其相關(guān)危險(xiǎn)因素的多元回歸分析[J];胃腸病學(xué)和肝病學(xué)雜志;2010年12期
5 何紹亞;向陽(yáng)生;何莉;;脂肪肝與代謝相關(guān)性疾病的關(guān)系[J];現(xiàn)代預(yù)防醫(yī)學(xué);2011年06期
6 向國(guó)卿;孟憲云;張浩;臺(tái)文霞;孟曉丹;王炳元;;脂肪肝相關(guān)危險(xiǎn)因素的評(píng)估[J];世界華人消化雜志;2009年10期
7 羅建文,白凈;超聲彈性成像的研究進(jìn)展[J];中國(guó)醫(yī)療器械信息;2005年05期
8 賀文,錢(qián)林學(xué),趙繼學(xué),馬大慶,馮捷,胡志海;CT定量診斷脂肪肝的臨床研究[J];中華放射學(xué)雜志;2001年11期
9 范建高,朱軍,李新建,李銳,戴菲,宋曉敏,陳蘭,李鋒,陳世耀;上海市成人脂肪肝患病率及其危險(xiǎn)因素流行病學(xué)調(diào)查[J];中華肝臟病雜志;2005年02期
10 中國(guó)肥胖問(wèn)題工作組數(shù)據(jù)匯總分析協(xié)作組;我國(guó)成人體重指數(shù)和腰圍對(duì)相關(guān)疾病危險(xiǎn)因素異常的預(yù)測(cè)價(jià)值:適宜體重指數(shù)和腰圍切點(diǎn)的研究[J];中華流行病學(xué)雜志;2002年01期
本文編號(hào):1999702
本文鏈接:http://sikaile.net/yixuelunwen/xiaohjib/1999702.html