本文選題：胃蛋白酶原 + 抗幽門螺桿菌Ig　； 參考：《中國現(xiàn)代醫(yī)學(xué)雜志》2015年05期

【摘要】：目的研究血清胃蛋白酶原(PG)與幽門螺桿菌(HP)抗體對十二指腸潰瘍的篩查價(jià)值。方法選取2007年11月~2012年9月,在該院體檢時(shí)發(fā)現(xiàn)的十二指腸潰瘍50例,健康對照組為同期體檢者,共50例,其中男女比例及年齡均與潰瘍組相同。采用膠乳增強(qiáng)免疫透射比濁法檢測血清胃蛋白酶原(PGⅠ、PGⅡ),并計(jì)算兩者比值PGⅠ/PGⅡ(PGR);利用酶聯(lián)免疫吸附試驗(yàn)法(ELISA)對受檢者血清進(jìn)行抗Hp-Ig G抗體檢測。結(jié)果潰瘍組中,PGⅠ與PGⅡ的濃度分別為(171.24±21.45)和(26.11±11.04)ng/ml,PGR為(8.18±1.09),PGⅠ、PGⅡ及PGR值明顯高于對照組(P0.05)。潰瘍組與對照組抗Hp-Ig G抗體陽性率分別為73.5%和20.6%,差異具有統(tǒng)計(jì)學(xué)意義(P0.05)�？笻p-Ig G陽性組的PGⅠ與PGⅡ值分別為(159.05±21.24)和(22.74±11.16)ng/ml,PGR為(6.97±2.14),明顯高于陰性組(P0.05)。結(jié)論異常血清胃蛋白酶原與抗Hp-Ig G抗體與十二指腸潰瘍密切相關(guān),并且可以作為潰瘍早期的篩查指標(biāo)。
[Abstract]:Objective to study the value of serum pepsinogen (PG) and Helicobacter pylori (HP) antibodies in the screening of duodenal ulcer. Methods from November 2007 to September 2012, 50 cases of duodenal ulcer were found in our hospital, and 50 cases of healthy control group were examined at the same time. The ratio of male and female and age were the same as those of ulcer group. Latex enhanced immunoturbidimetric assay was used to detect serum pepsinogen PG 鈪，

本文編號：1889011