本文選題：半夏厚樸湯 + 中西醫(yī)聯(lián)合治療　； 參考：《成都中醫(yī)藥大學(xué)》2015年碩士論文

【摘要】：目的：觀察半夏厚樸湯加味+蘭索拉唑片、枸櫞酸莫沙必利分散片聯(lián)合治療反流性食管炎(氣郁痰阻型)臨床療效。方法：研究對象為2014年1月—2014年12月就診于成都中醫(yī)藥大學(xué)附屬醫(yī)院消化內(nèi)科門診病人,符合納入及排除標(biāo)準(zhǔn)患者60例,隨機(jī)(抽簽法)分為兩組,其中中西醫(yī)組30例,給予中藥半夏厚樸湯加味+蘭索拉唑片、枸櫞酸莫沙必利分散片。西醫(yī)組30例,給予蘭索拉唑片+枸櫞酸莫沙必利分散片。治療周期均為8周。觀察兩組患者中醫(yī)證候評分、RDQ評分及胃鏡下食管黏膜的修復(fù)情況。記錄結(jié)果的數(shù)據(jù)用SPSS 17.0統(tǒng)計軟件進(jìn)行統(tǒng)計學(xué)分析。結(jié)果：治療前兩組患者的性別、年齡、病程、以及胃鏡下食管黏膜的情況等數(shù)據(jù)比較P0.05。治療后復(fù)查胃鏡,中西醫(yī)組治愈率為27%,總有效率達(dá)90%,西醫(yī)組治愈率為10%,總有效率為87%,二者比較P0.05。中醫(yī)證候療效比較,治療4周時,中西醫(yī)組總有效率為80%,西醫(yī)組總有效率為70%,P0.05；治療8周,中西醫(yī)組總有效率為97%,西醫(yī)組總有效率為87%, P0.05。中醫(yī)證候總積分比較,P0.05。RDQ評分比較：治療前兩組比較P0.05。4周時,中西醫(yī)組治療前后RDQ評分比較P0.05；西醫(yī)組治療前后RD)Q評分比較P0.05；但兩組比較P0.05。8周時,中西醫(yī)組治療前后RDQ評分比較P0.01,西醫(yī)組治療前后比較P0.05,治療后兩組RDQ評分比較P0.05。結(jié)論：中西醫(yī)聯(lián)合治療反流性食管炎(氣郁痰阻型)比純西醫(yī)治療更具有優(yōu)勢,并且安全有效,可以在辨證論治的基礎(chǔ)上在臨床推廣應(yīng)用,有進(jìn)一步深入研究的價值。
[Abstract]:Objective: to observe the clinical effect of Banxia Houpu decoction lansoprazole tablet and mosapride citrate dispersible tablet in the treatment of reflux esophagitis. Methods: from January 2014 to December 2014, 60 outpatients in the Department of Digestive Medicine, affiliated Hospital of Chengdu University of traditional Chinese Medicine, were randomly divided into two groups, including 30 cases in Chinese and western medicine group, 30 cases in traditional Chinese and western medicine group, and 60 cases in accordance with the criteria of inclusion and exclusion. Banxia Houpu decoction lansoprazole tablet, mosapride citrate dispersible tablets. In the western medicine group, 30 cases were treated with lansoprazole tablets and mosapride citrate dispersible tablets. The treatment cycle was 8 weeks. The RDQ score of TCM syndromes and the repair of esophageal mucosa under gastroscope were observed. The data recorded were analyzed by SPSS 17.0 statistical software. Results: the data of sex, age, course of disease, and the condition of esophagus mucosa under gastroscopy were compared between the two groups before treatment (P 0.05). After reexamination of gastroscope, the cure rate of TCM and Western medicine group was 27, the total effective rate was 90, the cure rate of western medicine group was 10, the total effective rate was 87, the comparison between them was P0.05. After 4 weeks of treatment, the total effective rate of traditional Chinese and western medicine group was 80 and the total effective rate of western medicine group was 70 P0.05; after 8 weeks treatment, the total effective rate of traditional Chinese and western medicine group was 97%, and the total effective rate of western medicine group was 87 and P 0.05 respectively. Comparison of the total score of TCM syndromes and P0.05.RDQ score: before and after treatment, the RDQ score of the two groups was compared with that of the control group (P0.05); the RD)Q score of the western medicine group was compared with that of the control group (P0.05); but the two groups were compared at P0.05.8 weeks. Before and after treatment, the RDQ score of the traditional Chinese and western medicine group was compared with that of the western medicine group (P0.05), and the RDQ score of the two groups was compared after the treatment (P0.05). Conclusion: the treatment of reflux esophagitis (Qi stagnation and phlegm obstruction type) with combination of traditional Chinese and Western medicine has more advantages than that of pure western medicine, and it is safe and effective. It can be popularized and applied in clinic on the basis of syndrome differentiation and has the value of further study.
【學(xué)位授予單位】：成都中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2015
【分類號】：R571

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