本文選題：重癥急性胰腺炎 + 胃腸動(dòng)力障礙��； 參考：《山東醫(yī)藥》2015年45期

【摘要】：急性胰腺炎尤其是重癥急性胰腺炎(SAP)患者早期常出現(xiàn)胃腸功能障礙和黏膜病變。SAP并胃腸動(dòng)力障礙與神經(jīng)因素、NO過量、胃腸激素變化、炎癥介質(zhì)過量表達(dá)、消化系Cajal間質(zhì)細(xì)胞缺失、胰腺炎相關(guān)性腹水等有關(guān),SAP并發(fā)消化性潰瘍的機(jī)制仍不完全清楚,多數(shù)研究認(rèn)為與胰腺本身病變所致的黏膜損害因素加重和抗損害能力的削弱有關(guān)。胰腺壞死、膿毒癥、APACHEⅡ評分、胰腺膿腫、胰腺囊腫和器官衰竭均是SAP合并消化道出血的高危因素。
[Abstract]:In patients with acute pancreatitis, especially severe acute pancreatitis (SAP), gastrointestinal dysfunction and mucosal lesion. SAP with gastrointestinal motility disorder and neurologic factors such as no excess, gastrointestinal hormone changes, and inflammatory mediators overexpression were often found in the early stage of acute pancreatitis, especially severe acute pancreatitis (SAP). The mechanisms associated with peptic ulcer in digestive system, such as interstitial cell loss and pancreatitis associated ascites, are still not fully understood. Most studies suggest that the mechanism is related to the exacerbation of mucosal damage caused by pancreatic lesions and the weakening of the ability to resist injury. Pancreatic necrosis, sepsis, Apache 鈪，

本文編號(hào)：1812231