慢性乙型肝炎肝臟超聲半定量評(píng)分及其他指標(biāo)與肝功能相關(guān)性研究
發(fā)布時(shí)間:2018-04-27 14:00
本文選題:超聲 + 超聲評(píng)分 ; 參考:《廣西醫(yī)科大學(xué)》2014年碩士論文
【摘要】:目的:探討慢性乙型肝炎(Chronic hepatitis B, C H B)患者不同肝臟超聲評(píng)分組之間肝大小指數(shù)、肝門靜脈內(nèi)徑及流速、肝功能指標(biāo)的差異,并分析超聲評(píng)分、肝大小指數(shù)、門靜脈內(nèi)徑及流速與肝功能指標(biāo)的相關(guān)性。 方法:對(duì)67例慢性乙型肝炎患者(男性患者43例,女性患者24例,年齡22-60歲,平均年齡48.3士9.6歲)的肝包膜、邊緣角、實(shí)質(zhì)、靜脈壁及膽囊壁回聲進(jìn)行超聲半定量評(píng)分,并測(cè)量肝大小指數(shù)、門靜脈主干內(nèi)徑、門靜脈主干血流速度。分析肝臟不同超聲評(píng)分組之間的肝功能各項(xiàng)指標(biāo)、肝臟大小指數(shù)、門靜脈內(nèi)徑及血流速度的差異;研究超聲評(píng)分、肝臟大小指數(shù)、門靜脈內(nèi)徑及血流與肝功能指標(biāo)之間的相關(guān)性。 結(jié)果:①不同超聲評(píng)分組的肝大小指數(shù)、門靜脈內(nèi)徑及流速、肝功能指標(biāo)比較差異有統(tǒng)計(jì)學(xué)意義(P0.05)。②血清總蛋白(Total Protein.TP)、清蛋白(Albumin.A l b)、前清蛋白(Prealbumin、P A)、膽堿酯酶(Cholinesterase.C H E)與超聲評(píng)分、門靜脈內(nèi)徑負(fù)相關(guān);與肝大小指數(shù)、門靜脈流速正相關(guān)(|r|均0.4,P0.05)。③血清堿性磷酸酶(Alkaline phosphatase.A l p)與超聲評(píng)分、門靜脈內(nèi)徑正相關(guān);與肝大小指數(shù)、門靜脈流速負(fù)相關(guān)(|r|均0.4,PO.05)。④超聲評(píng)分與TP、Alb、P A、C H E、A l p的相關(guān)系數(shù)分別為r=-0.634、r=-0.761、r=-0.877、r=-0.763、r=0.722,相關(guān)系數(shù)較其他超聲指標(biāo)高。 結(jié)論:肝臟超聲評(píng)分、肝臟大小指數(shù)、肝門靜脈內(nèi)徑及血流速度與肝功能指標(biāo)變化有一定相關(guān)性,其中肝臟超聲評(píng)分高低與肝功能關(guān)系更為密切。
[Abstract]:Objective: to study the difference of liver size index, portal vein diameter and velocity, liver function index between different liver ultrasound scoring groups in chronic hepatitis B patients with chronic hepatitis B hepatitis B (C-H B), and to analyze the ultrasonic score and liver size index. Correlation between portal vein diameter and flow velocity and liver function. Methods: the echo of liver capsule, marginal angle, parenchyma, venous wall and gallbladder wall in 67 patients with chronic hepatitis B (43 male and 24 female, aged 22-60 years, mean age 48.3 鹵9.6 years) were assessed by ultrasonic semi-quantitative method. The liver size index, the diameter of the main portal vein and the blood flow velocity of the main portal vein were measured. To analyze the differences of liver function indexes, liver size index, portal vein diameter and blood flow velocity among different ultrasound scoring groups, to study the ultrasound score, liver size index, liver size index, liver size index, liver size index, liver size index, Correlation between portal vein diameter and blood flow and liver function. Results there were significant differences in liver size index, portal vein diameter and velocity of blood flow, liver function index, total protein. TPN, Albumin.AlbBN, prealbumin P, cholinesterase.C H and ultrasound scores in different ultrasound score groups. There was a positive correlation between portal vein diameter and liver size index, portal vein velocity (r = 0.4p 0.053.Serum alkaline phosphatase Alkaline phosphatase.A l p) and ultrasonic score, portal vein diameter, liver size index, liver size index, liver size index, There was a negative correlation between the portal vein velocity (r = 0.4) PO.054.The correlation coefficient between the ultrasound score and the TPAb P Agna C H EJ Alp was r = -0.634g ~ (-1) ~ (-1) ~ (-0.761) ~ (-1) ~ (-1) ~ (-0.877) ~ (-1) ~ (-1) ~ (-0.763) ~ (-1), and the correlation coefficient was higher than that of other ultrasound indexes. Conclusion: liver ultrasound score, liver size index, hepatic portal vein diameter and blood flow velocity have some correlation with liver function index, and liver ultrasound score is more closely related to liver function.
【學(xué)位授予單位】:廣西醫(yī)科大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2014
【分類號(hào)】:R512.62;R445.1
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