本文選題：重癥急性胰腺炎 + 谷氨酰胺　； 參考：《中國老年學(xué)雜志》2015年12期

【摘要】：目的探討早期腸內(nèi)營(yíng)養(yǎng)(EN)聯(lián)合谷氨酰胺對(duì)老年重癥急性胰腺炎(SAP)營(yíng)養(yǎng)狀況的影響。方法將該院收治的90例老年SAP患者隨機(jī)分為觀察組與對(duì)照組各45例,在基礎(chǔ)治療的基礎(chǔ)上,觀察組給予早期EN聯(lián)合谷氨酰胺營(yíng)養(yǎng)干預(yù)支持,對(duì)照組給予完全胃腸外營(yíng)養(yǎng)(TPN)。觀察并比較兩組患者入院時(shí)、營(yíng)養(yǎng)支持7、14 d后的血淀粉酶、尿淀粉酶、急性生理學(xué)及慢性健康狀況(APACHE-Ⅱ)評(píng)分、Ranson評(píng)分及血清白蛋白(ALB)、血清前白蛋白(PA)、轉(zhuǎn)鐵蛋白(TRF)及體重變化情況;并比較兩組患者平均住院天數(shù)及并發(fā)癥發(fā)生率。結(jié)果兩組患者治療7、14 d后,血淀粉酶、尿淀粉酶、APACHE-Ⅱ評(píng)分、Ranson評(píng)分均較入院時(shí)顯著下降(P0.05);觀察組患者治療7、14 d后上述指標(biāo)明顯低于對(duì)照組同期(P0.05);觀察組患者治療7、14 d后ALB、PA、TRF及體重均高于對(duì)照組(P0.05);觀察組平均住院天數(shù)顯著短于對(duì)照組,其并發(fā)癥發(fā)生率低于對(duì)照組。結(jié)論早期EN聯(lián)合谷氨酰胺營(yíng)養(yǎng)支持干預(yù)較TPN在治療老年SAP中能更有效地緩解機(jī)體高分解代謝,明顯改善患者營(yíng)養(yǎng)狀況,有效減少并發(fā)癥發(fā)生,值得臨床重視。
[Abstract]:Objective to investigate the effect of early enteral nutrition (en) combined with glutamine on the nutritional status of elderly patients with severe acute pancreatitis (SAP).Methods 90 elderly patients with SAP were randomly divided into two groups: the observation group (n = 45) and the control group (n = 45). On the basis of basic treatment, the observation group was given early en combined with glutamine nutrition intervention support, and the control group was given complete parenteral nutrition.The serum amylase and urine amylase were observed and compared between the two groups after 7d of nutrition support.Acute Physiology and chronic Health status (APACHE- 鈪，

本文編號(hào)：1765951