本文選題：重癥急性胰腺炎 + 銅綠假單胞菌��； 參考：《中國現(xiàn)代醫(yī)學(xué)雜志》2017年12期

【摘要】：目的探討重癥急性胰腺炎(SAP)患者并發(fā)多重耐藥性銅綠假單胞菌(PAE)感染的危險因素及其耐藥性分析。方法回顧性納入該院2006年1月-2016年12月收治的SAP患者102例。根據(jù)是否合并多重耐藥性PAE感染分為感染組(17例)和對照組(85例),分析兩組患者一般情況,采用Logistic回歸分析患者感染多重耐藥性PAE的危險因素。結(jié)果 SAP合并多重耐藥性PAE感染的比例為16.67%。兩組患者性別、病因及合并疾病發(fā)生率比較,差異無統(tǒng)計學(xué)意義(P0.05)。感染組年齡、CT危重度評分(CTSI)及SAP危重度分級高于對照組(P0.05);急性期急性呼吸窘迫綜合征(ARDS)和休克發(fā)生率高于對照組(P0.05);入院時急性生理功能和慢性健康狀況評分Ⅱ(APACHEⅡ)評分更高;急性期重癥監(jiān)護病房(ICU)住院天數(shù)更長。多因素Logistic回歸分析發(fā)現(xiàn),PAE感染的危險因素包括CTSI、SAP危重度、急性期出現(xiàn)ARDS、入院APACHEⅡ評分過高及急性期過長的ICU暴露時間(P0.05)。臨床預(yù)后方面,相比于對照組,感染組感染期休克和膿毒癥發(fā)生率高于對照組;ICU住院天數(shù)和總住院天數(shù)高于對照組,但兩組死亡率比較差異無統(tǒng)計學(xué)意義。結(jié)論 SAP患者PAE感染的危險因素包括CTSI、SAP危重度、急性期ARDS、過長的ICU暴露時間及入院APACHEⅡ評分過高。
[Abstract]:Objective to investigate the risk factors and drug resistance of multidrug resistant Pseudomonas aeruginosa (PAE) infection in patients with severe acute pancreatitis (SAP).Methods 102 cases of SAP were retrospectively included in our hospital from January 2006 to December 2016.According to whether the patients were complicated with multidrug resistant PAE infection, they were divided into two groups: infection group (n = 17) and control group (n = 85). The general conditions of the two groups were analyzed, and the risk factors of infection with multidrug resistance PAE were analyzed by Logistic regression analysis.Results the proportion of SAP complicated with multidrug resistant PAE infection was 16.67%.There was no significant difference in sex, etiology and incidence of complicated diseases between the two groups (P 0.05).The scores of CTSI and SAP in the infection group were higher than those in the control group (P 0.05), the incidence of acute respiratory distress syndrome (ARDS) and shock were higher than those in the control group (P 0.05), and the scores of acute physiological function and chronic health status 鈪，

本文編號：1753730