真實(shí)穩(wěn)態(tài)進(jìn)動(dòng)快速成像在脂肪肝診斷中的臨床應(yīng)用
發(fā)布時(shí)間:2018-04-09 18:34
本文選題:脂肪肝 切入點(diǎn):磁共振成像 出處:《放射學(xué)實(shí)踐》2017年06期
【摘要】:目的:探討真實(shí)穩(wěn)態(tài)進(jìn)動(dòng)快速成像(true-FISP)序列在脂肪肝診斷中的臨床應(yīng)用價(jià)值。方法:回顧性分析528例患者的MRI和CT影像學(xué)表現(xiàn),測(cè)量true-FISP序列上肝/腰大肌信號(hào)強(qiáng)度比值(S_(L/PM)),并與非增強(qiáng)CT檢查肝/脾CT值比值(CT_(L/S))結(jié)果對(duì)比。結(jié)果:528例患者CT檢查診斷脂肪肝陽性病例組107例,陰性組421例,兩組間肝臟CT值(CT_L)、CT_(L/S)、S_(L/PM)均有顯著性差異,脾臟CT值(CT_S)無統(tǒng)計(jì)學(xué)差異,CT_L、CT_S、CT_(L/S)、S_(L/PM)分別為(38.88±12.66)HU、(60.80±5.66)HU(t=-17.46,P0.001);(53.22±3.85)、(52.49±3.65)(t=1.832,P=0.07);(0.73±0.24),(1.16±0.10)(t=-18.43,P0.001);(0.73±0.24)、(1.56±0.28)(t=-23.02,P0.001)。S_(L/PM)與CT_(L/S)正相關(guān)(r=0.43,P0.001)。S_(L/PM)最佳診斷分界點(diǎn)為1.14,ROC曲線下面積(AUC)為0.949(P0.001),Kappa值0.797(P0.001),敏感度為88.8%,特異度為94.3%,誤診率5.7%、漏診率11.2%、總的符合率93.2%、Youden指數(shù)83.1%、比數(shù)積130.95、陽性預(yù)測(cè)值88.8%、陰性預(yù)測(cè)值94.3%。對(duì)輕、中、重度脂肪肝診斷的AUC分別為0.857、0.942、0.983(P0.001),敏感度82.6%、100%、100%,特異度86.5%、80.5%、80.2%。結(jié)論:true-FISP序列對(duì)脂肪肝的診斷具有重要的臨床應(yīng)用價(jià)值,當(dāng)發(fā)現(xiàn)肝臟信號(hào)強(qiáng)度減低且接近或低于腰大肌時(shí)可作為診斷標(biāo)準(zhǔn),對(duì)中、重度脂肪肝的診斷效果高于輕度脂肪肝。
[Abstract]:Objective: to evaluate the clinical value of true steady-state precession fast imaging (FISP) sequence in the diagnosis of fatty liver.Methods: the MRI and CT imaging findings of 528 patients were retrospectively analyzed. The signal intensity ratio of liver / psoas major muscle on true-FISP sequence was measured and compared with that of non-enhanced CT.Results there were significant differences in CT value of liver CT between the two groups in 107 cases of fatty liver positive cases and 421 cases of negative group. There was a significant difference between the two groups.鑴捐剰CT鍊,
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