本文選題：急性胰腺炎　切入點(diǎn)：持續(xù)高容量血液濾過　出處：《山東醫(yī)藥》2015年35期

【摘要】：目的觀察持續(xù)高容量血液濾過(HFD)聯(lián)合胸腹腔引流在重癥急性胰腺炎(SAP)治療中的應(yīng)用效果。方法 51例SAP患者隨機(jī)分為觀察組36例和對照組15例,兩組均采用基礎(chǔ)治療,觀察組在此基礎(chǔ)上采用HFD聯(lián)合胸腹腔引流。采用ELISA法檢測兩組IL-6,乳膠增強(qiáng)免疫法檢測C反應(yīng)蛋白(CRP),記錄腹痛消失、腹脹緩解時間及CT嚴(yán)重程度評分、急性生理學(xué)和慢性健康狀況評分(APACHEⅡ評分)。結(jié)果與同組治療前比較,兩組治療3 d IL-6、CRP水平降低(P均0.05);與對照組比較,觀察組治療3 d IL-6、CRP水平降低(P均0.05)。與對照組比較,觀察組腹痛持續(xù)、腹脹緩解時間短(P均0.05)。與同組治療前比較,兩組治療3、14 d CT嚴(yán)重程度評分及APACHEⅡ評分降低(P均0.05);與對照組比較,觀察組治療3、14 d CT嚴(yán)重程度評分及APACHEⅡ評分降低(P均0.05)。結(jié)論 HFD聯(lián)合胸腹腔液體引流用于SAP治療效果較好。
[Abstract]:Objective to observe the effect of continuous high volume hemofiltration combined with chest and abdominal drainage in the treatment of severe acute pancreatitis (SAP). Methods 51 patients with SAP were randomly divided into observation group (n = 36) and control group (n = 15). On this basis, HFD combined with chest and abdominal drainage was used in the observation group, IL-6 was detected by ELISA method, C-reactive protein (CRP) was detected by emulsion enhanced immunoassay, abdominal pain disappeared, abdominal distension remission time and CT severity score were recorded. Results compared with the same group before treatment, the levels of IL-6 and CRP in the two groups decreased by 0.05% on the 3rd day after treatment, compared with the control group, the levels of IL-6 and CRP in the observation group were lower than those in the control group on the 3rd day after treatment, and the levels of IL-6 and CRP in the observation group were lower than those in the control group, and the levels of IL-6 and CRP in the observation group were lower than those in the control group. Compared with the control group, the CT severity score and APACHE 鈪，

本文編號：1672867