本文選題：老年人　切入點(diǎn)：功能性便秘　出處：《上海醫(yī)學(xué)》2017年03期

【摘要】：目的評價(jià)垂直律動(dòng)治療老年功能性便秘患者的臨床療效及其安全性。方法選取68例老年功能性便秘患者,隨機(jī)分入對照組(維持繼往藥物治療)和垂直律動(dòng)組(在維持繼往藥物治療的基礎(chǔ)上進(jìn)行全身重直律動(dòng)訓(xùn)練),療程均為6周。分別于治療前和療程結(jié)束后1周內(nèi)記錄患者的排便情況,包括大便性狀(Bristol評分)、每周排便次數(shù)、排便時(shí)間和便秘患者的生活質(zhì)量評估(PAC-QOL)量表評分,并測定血常規(guī)、肝功能[天冬氨酸轉(zhuǎn)氨酶(AST)、丙氨酸轉(zhuǎn)氨酶(ALT)、白蛋白]、腎功能(肌酐、尿酸)、血電解質(zhì)(鈉離子、鉀離子)指標(biāo)。觀察并記錄治療期間不良反應(yīng)(包括腹痛、腹脹、腹瀉、嘔吐等)發(fā)生情況。結(jié)果垂直律動(dòng)組治療后的每周排便次數(shù)顯著多于同組治療前(P0.05),排便時(shí)間顯著短于同組治療前(P0.05),Bristol評分顯著高于同組治療前(P0.05),PAC--QOI,量表評分顯著低于同組治療前(P0.05);對照組治療后的排便時(shí)間顯著短于同組治療前(P0.05),PAC-QOL量表評分顯著低于同組治療前(P0.05)。垂直律動(dòng)組治療后的每周排便次數(shù)顯著多于對照組治療后(P0.05),排便時(shí)間顯著短于對照組治療后(P0.05),Bristol評分顯著高于對照組治療后(P0.05),PAC-QOL量表評分顯著低于對照組治療后(P0.05)。兩組內(nèi)治療前后紅細(xì)胞計(jì)數(shù)、白細(xì)胞計(jì)數(shù),以及AST、ALT、白蛋白、尿酸、肌酐、鈉離子、鉀離子水平的差異均無統(tǒng)計(jì)學(xué)意義(P值均0.05);兩組間治療前和治療后上述各項(xiàng)指標(biāo)的差異亦均無統(tǒng)計(jì)學(xué)意義(P值均0.05)。治療期間兩組均無1例患者發(fā)生腹痛、腹脹、腹瀉、嘔吐等不良反應(yīng)。結(jié)論垂直律動(dòng)治療能改善老年功能性便秘患者的癥狀,提高其生活質(zhì)量。
[Abstract]:Objective to evaluate the clinical efficacy and safety of perpendicular rhythm in the treatment of senile functional constipation. They were randomly divided into two groups: control group (maintenance followed by drug therapy) and vertical rhythmic group (after maintenance of drug therapy). The course of treatment was 6 weeks. The course of treatment was 6 weeks before and 1 week after the end of the course of treatment, respectively. Record the patient's defecation, These include stool trait Bristol score, weekly defecation times, defecation time and quality of life assessment of constipation patients (PAC-QOLscale), blood routine, liver function [aspartate transaminase (AST), alanine aminotransferase (alt), albumin], renal function (creatinine, creatinine), and renal function (creatinine). Uric acid, blood electrolytes (sodium, potassium). Adverse reactions (including abdominal pain, abdominal distension, diarrhea) during treatment were observed and recorded. Results the frequency of defecation per week in the perpendicular rhythmic group was significantly higher than that in the same group before treatment, and the defecation time was significantly shorter than that in the same group before treatment. The score of Bristol was significantly higher than that in the same group before treatment, and the score of the scale was significantly lower than that of the same group before treatment. The defecation time after treatment in the control group was significantly shorter than that in the control group before treatment, and the score of PAC-QOL in the control group was significantly lower than that in the same group before treatment. The times of defecation per week in the perpendicular rhythm group were significantly higher than those in the control group after treatment, and the defecation time in the perpendicular rhythm group was significantly higher than that in the control group after treatment. The score of Bristol after treatment in control group was significantly lower than that in control group after treatment, and the score of PAC-QOL was significantly lower than that in control group before and after treatment, and the erythrocyte count before and after treatment in both groups was significantly lower than that in control group. White blood cell count, as well as alt, albumin, uric acid, creatinine, sodium ions, There was no significant difference in potassium level between the two groups before and after treatment, and there was no significant difference in P value between the two groups before and after treatment. During the treatment period, there was no abdominal pain, abdominal distension, diarrhea in both groups, and there was no significant difference between the two groups in abdominal pain, abdominal distension and diarrhea. Conclusion Vertical rhythm therapy can improve the symptoms and quality of life of senile patients with functional constipation.
【作者單位】： 復(fù)旦大學(xué)附屬華東醫(yī)院康復(fù)醫(yī)學(xué)科;復(fù)旦大學(xué)附屬華東醫(yī)院推拿科;復(fù)旦大學(xué)附屬華東醫(yī)院消化科;上海中醫(yī)藥大學(xué)護(hù)理學(xué)院;
【基金】：上海市科學(xué)技術(shù)委員會(huì)課題(15411965200) 上海市衛(wèi)生和計(jì)劃生育委員會(huì)中醫(yī)藥科研專項(xiàng)(2016LP021)資助項(xiàng)目
【分類號】：R574.62

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