本文選題：急性腸功能衰竭　切入點：加味增液承氣湯　出處：《青島大學(xué)》2014年碩士論文　論文類型：學(xué)位論文

【摘要】：目的：對加味增液承氣湯灌腸治療急性腸功能衰竭的臨床療效進(jìn)行初步探討研究,旨在為急性腸功能衰竭的中醫(yī)臨床治療提供一定參考。 方法：選擇我科室于2013年1-12月期間收治的48例急性腸功能衰竭患者作為本研究對象,將其按數(shù)字隨機(jī)原則分為治療組與對照組各24例,所有患者在入院后均常規(guī)治療原發(fā)病,并給予對癥支持治療,治療組治療方法在此基礎(chǔ)上再加行加味增液承氣湯水煎液灌腸治療,觀察并記錄兩組患者在接受治療后的首次排便時間、腹痛腹脹緩解時間、腸鳴音恢復(fù)時間以及住院時間等,另分別于治療前與治療后7d考察患者的急性生理與慢性健康狀況評分Ⅱ(APACHE Ⅱ評分)以及相關(guān)炎癥反應(yīng)指標(biāo)白細(xì)胞計數(shù)(WBC)與血清C-反應(yīng)蛋白(CRP)。 結(jié)果：治療組與對照組在性別、年齡、治療前APACHE Ⅱ評分方面均無顯著性差異(P0.05)；組間比較治療前炎癥反應(yīng)指標(biāo)也無統(tǒng)計學(xué)意義(twBC=0.814, PWBC=0.2060.05; tCRP=0.887, PCRP=0.2010.05),兩組患者具可比性；治療后比較兩組患者的首次排便時間、腹痛腹脹緩解時間、腸鳴音恢復(fù)時間以及住院時間均以觀察組顯著更短,與對照組比較均有統(tǒng)計學(xué)意義(P0.05)；治療前兩組患者APACHEII評分比較無統(tǒng)計學(xué)意義(P0.05),治療后7d治療組APACHE Ⅱ評分顯著低于對照組(P0.01)；治療過程中治療組與對照組少數(shù)病例出現(xiàn)輕微腹瀉,但不影響用藥,此外無其他明顯任何不良反應(yīng)出現(xiàn)。 結(jié)論：加味增液承氣湯灌腸治療急性腸功能衰竭不僅可顯著地縮短患者的首次排便時間、腹痛腹脹緩解時間、腸鳴音恢復(fù)時間以及住院時間,同時也可顯著降低APACHE Ⅱ評分,臨床療效滿意,建議進(jìn)一步開展大宗病例的臨床研究。
[Abstract]:Objective: To investigate the clinical efficacy of Jiawei Zengli Chengqi Decoction enema in the treatment of acute intestinal failure, aiming to provide certain reference for clinical treatment of acute intestinal failure in TCM.
Methods: 48 cases of acute intestinal failure patients in our department treated during 2013 1-12 months as the research object, according to its figures were randomly divided into treatment group and control group of 24 cases, all patients in the hospital were the routine treatment of the primary disease, and given symptomatic treatment, the treatment group based method then by Jiaweizengyechengqi Decoction Decoction enema, observe and record the two groups of patients after treatment of the first defecation time, abdominal pain relief time, bowel sound recovery time and hospital stay, the other respectively before and after the treatment of 7D patients with acute physiology and chronic health evaluation II (APACHE score) and related indicators of inflammation of white blood cell count (WBC) with the serum C- reactive protein (CRP).
Results: the treatment group and control group in gender, age, before treatment APACHE score showed no significant difference (P0.05); the treatment group compared with no significant inflammatory reaction index (twBC=0.814, PWBC=0.2060.05; tCRP=0.887, PCRP=0.2010.05), the two groups were comparable; after treatment were compared between the two groups the first defecation time, abdominal pain relief time, bowel sound recovery time and hospitalization time was significantly shorter in the observation group, and control group were statistically significant (P0.05); two groups of patients before treatment APACHEII score was not statistically significant (P0.05), 7d treatment group after treatment APACHE score was significantly lower than the control group (P0.01) in the course of treatment; the treatment group and the control group a few cases had mild diarrhea, but does not affect the use, in addition there is no other obvious any adverse reactions.
Conclusion: Jiaweizengyechengqi Decoction enema in the treatment of acute intestinal failure not only can significantly shorten the patient's first defecation time, abdominal pain relief time, bowel sound recovery time and hospitalization time, but also can significantly reduce APACHE score, clinical efficacy, clinical studies suggest that further development of the bulk of cases.

【學(xué)位授予單位】：青島大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2014
【分類號】：R574

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本文編號：1649693