本文選題：胃食管反流病　切入點(diǎn)：睡眠呼吸暫停低通氣綜合征　出處：《寧夏醫(yī)科大學(xué)》2014年碩士論文　論文類型：學(xué)位論文

【摘要】：目的研究調(diào)查胃食管反流�。℅ERD）與阻塞型睡眠呼吸暫停低通氣綜合征(OSAHS)的關(guān)系。 材料與方法收集260例OSAHS患者，其中男性194例、女性66例，對所收集的患者進(jìn)行胃食管反流病問卷調(diào)查，分為伴有GERD組119例，無GERD組141例，對伴有GERD組和無GERD組的患者進(jìn)行睡眠呼吸暫停低通氣指數(shù)（AHI）、體重指數(shù)（BMI）的比較。同時對不同分度的OSAHA患者進(jìn)行胃食管反流癥狀積分的比較。 研究結(jié)果260例OSAHS患者中伴有GERD組患者為119例，約占45.77%（119/260），不伴有GERD組患者為141例，約占54.23%（141/260）；伴有GERD組中男性99例(83.19%)，女性20例(16.80%)，不伴有GERD組男性95例(67.38%)，女性46例(32.62%)，伴有GERD組與不伴有GERD組在性別方面有統(tǒng)計學(xué)意義(χ2=8.524，，P=0.004)；伴有GERD的OSAHS患者中，以年齡大于47歲患者為主，占78.1%；同時伴有GERD組的OSAHS患者比無GERD組的OSAHS患者的體重指數(shù)（BMI）及睡眠呼吸暫停低通氣指數(shù)（AHI）均高，P＜0.05，提示結(jié)果有統(tǒng)計學(xué)意義；不同分度的OSAHS患者中，重度OSAHS患者的GERD積分較中度OSAHS患者高，中度OSAHS患者的GERD積分較輕度OSAHS患者高，P＜0.05，結(jié)果具有統(tǒng)計學(xué)意義。 結(jié)論1.伴有GERD的OSAHS患者以中老年、肥胖男性居多； 2. OSAHS患者中GERD的發(fā)病比例較高，約占45.77%； 3．在OSAHS患者中，伴有GERD組的睡眠呼吸暫停指數(shù)（AHI）較不伴有GERD組患者高； 4.不同分度的OSAHS患者隨著病情的嚴(yán)重程度增加，其GERD積分也加重，二者成正相關(guān)。
[Abstract]:Objective to investigate the relationship between gastroesophageal reflux disease (GERD) and obstructive sleep apnea hypopnea syndrome (OSAHS). Materials and methods 260 patients with OSAHS, including 194 males and 66 females, were investigated with gastroesophageal reflux disease (GERD). The patients were divided into GERD group (119 cases) and no GERD group (141 cases). The apnea hypopnea index (AHI) and body mass index (BMI) were compared between the patients with GERD and those without GERD. The scores of gastroesophageal reflux symptoms were compared among OSAHA patients with different degrees of OSAHA. Results among the 260 patients with OSAHS, 119 were in the GERD group, accounting for 45.77% of 119 / 260 cases, and 141 cases in the non-#en2# group. In the GERD group, there were 99 males (83.19%), 20 females (16.80%), 95 males in the GERD group (67.3838), 46 females (32.62%), and there were significant differences in sex between the GERD group and the GERD group (蠂 28.524 P 0.004; in OSAHS patients with GERD, the majority were older than 47 years old). At the same time, the body mass index (BMI) and sleep apnea hypopnea index (AHII) in OSAHS patients with GERD were significantly higher than those in OSAHS patients without GERD (P < 0.05). The GERD score of severe OSAHS patients was higher than that of moderate OSAHS patients, and the GERD score of moderate OSAHS patients was higher than that of mild OSAHS patients (P < 0.05). Conclusion 1. The middle and old age patients with OSAHS with GERD are mostly obese men. 2. 2. The incidence of GERD was higher in OSAHS patients, accounting for 45.77%. 3. In OSAHS patients, the sleep apnea index (AHII) in GERD group was higher than that in non-#en2# group. 4. The GERD score of OSAHS patients with different grades increased with the severity of the disease, which was positively correlated with the severity of the disease.
【學(xué)位授予單位】：寧夏醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2014
【分類號】：R571

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