本文選題：糖尿病性視網(wǎng)膜病變黃斑改變 + OCT與FFA聯(lián)合檢查�。� 參考：《內(nèi)蒙古醫(yī)學(xué)雜志》2016年09期

【摘要】：目的本研究的目的在于應(yīng)用光學(xué)相干斷層掃描(OCT)以及眼底熒光血管造影(FFA),作為兩種客觀的檢查手段觀察糖尿病性視網(wǎng)膜病變(DR)在各個(gè)階段的黃斑改變,探討DR年齡、性別、糖尿病病程對(duì)黃斑區(qū)的影響。方法應(yīng)用蔡司3代時(shí)域光學(xué)相干斷層掃描(OCT)OCTA 6.01軟件版本分析,應(yīng)用重慶康華眼底熒光造影(FFA),對(duì)123例246只眼DR患者進(jìn)行檢查,并按年齡、性別及病程年限分組。結(jié)果123例246只眼DR患者中,20例40只眼,年齡25~85歲,男14例,女6例,病程1~10年,OCT觀察無(wú)明顯糖尿病性黃斑病變,FFA后極部無(wú)明顯視網(wǎng)膜增厚或硬性滲出。36例72只眼,年齡31~81歲,男16例,女20例,病程1~30年,OCT觀察輕度糖尿病性黃斑病變,FFA觀察后極部存在部分視網(wǎng)膜增厚或硬性滲出,但遠(yuǎn)離黃斑中心。32例64只眼,年齡38~78歲,男10例,女22例,糖尿病史4~30年,OCT觀察中度糖尿病性黃斑,FFA觀察視網(wǎng)膜增厚或硬性滲出接近黃斑但未涉及黃斑中心。35例70只眼,年齡27~76歲,男11例,女24例,糖尿病史3~32年,OCT觀察重度糖尿病性黃斑病變,FFA觀察視網(wǎng)膜增厚或硬性滲出涉及黃斑中心。結(jié)論 DR在各個(gè)階段,其中,發(fā)病8~20年間、年齡45~65歲之間、性別間,差異無(wú)統(tǒng)計(jì)學(xué)意義,DR發(fā)展成視網(wǎng)膜病變、黃斑改變等增殖性糖尿病性視網(wǎng)膜病變(PDR)的幾率更高,病情發(fā)展更快,同時(shí)進(jìn)一步證實(shí)FFA與OCT聯(lián)合檢查,對(duì)于判斷DR病變,發(fā)展階段及嚴(yán)重程度至關(guān)重要。
[Abstract]:Objective to investigate the macular changes of diabetic retinopathy in different stages by using optical coherence tomography (Oct) and fundus fluorescein angiography (FFAA), and to investigate the age and sex of Dr.The effect of the course of diabetes on macular area.Methods A software version of OCTA 6.01 was used to analyze OCTA 6.01 of Zeiss' 3rd generation optical coherence tomography. 123 patients (246 eyes) with Dr were examined by FFAA of Chongqing Kanghua fundus fluorescein angiography. The patients were divided into three groups according to age, sex and duration of disease.Results among the 246 eyes of 123 patients with Dr, 20 eyes (40 eyes), aged 2585 years, 14 males and 6 females, underwent Oct for 1 ~ 10 years. There was no obvious retinal thickening or hard exudation after FFA in 72 eyes of 36 patients (age 31: 81).16 males and 20 females were observed by Oct for 1 ~ 30 years. Partial retinal thickening or rigid exudation was observed in the posterior pole of FFA. However, 64 eyes were located far away from the center of macula in 64 eyes, aged 38 ~ 78 years, 10 males and 22 females.Oct from 4 to 30 years of history of diabetes, FFA of moderate diabetic macular macula was observed in 70 eyes of 35 cases (age 2776 years) with retinal thickening or rigid exudation close to macula but not involved in the center of macula. There were 11 males and 24 females.Observation of severe diabetic macular lesions with Oct for 3 ~ 32 years FFA was used to observe retinal thickening or rigid exudation involving macular center.Conclusion Dr is more likely to develop into retinopathy, such as macular change, proliferative diabetic retinopathy (PDR) in 820 years, between 45 and 65 years of age, and there is no significant difference between the sexes.At the same time, the combined examination of FFA and OCT is very important to judge the pathological changes, development stage and severity of Dr.
【作者單位】： 呼倫貝爾市人民醫(yī)院眼科;
【分類號(hào)】：R587.2;R774.1

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