【摘要】：目的研究仙靈骨葆膠囊聯(lián)合經(jīng)皮椎體后凸成形術(shù)(PKP)技術(shù)對老年骨質(zhì)疏松脊柱壓縮性骨折的療效。方法采用臨床觀察的方法,觀察研究武漢市第一醫(yī)院骨傷科2013年6月至2014年10月之間老年骨質(zhì)疏松患者因脊柱壓縮性骨折行PKP手術(shù)及抗骨質(zhì)疏松治療病例,選取80例病例,根據(jù)患者采取治療方法的不同,分為實驗組(中藥組)和對照組(西藥組)。實驗組40例病例,其中男15例,女25例,治療方法為:行PKP手術(shù)之后定期服用口服中成藥仙靈骨葆膠囊+鈣劑治療(實驗組);對照組40例,其中男16例,女24例,治療方法為行PKP手術(shù)后定期服用阿倫磷酸鈉+鈣劑治療(對照組:已知療效確切安全)。對兩組病例進行追蹤隨訪,觀察并記錄各組病例PKP手術(shù)術(shù)前、手術(shù)后、服藥治療一個月、服藥治療三個月、服藥治療半年的JOA評分、疼痛評分(采用視覺模擬評分法(VAS)評級進行評分)、骨密度等數(shù)據(jù)。比較分析各組實驗數(shù)據(jù)。結(jié)果兩組病例PKP手術(shù)術(shù)前、手術(shù)后、服藥治療一個月、服藥治療三個月、服藥治療半年的JOA評分、VAS評分、骨密度無顯著的統(tǒng)計學意義(P0.05)。結(jié)論仙靈骨葆結(jié)合PKP技術(shù)對老年骨質(zhì)疏松脊柱壓縮性骨折確有療效且安全可靠。
[Abstract]:Objective to study the efficacy of Xianling Gubao capsule combined with percutaneous kyphoplasty (PKP) in the treatment of senile osteoporotic spinal compression fracture. Methods Clinical observation was used to observe and study the PKP operation and anti-osteoporosis treatment in elderly patients with osteoporosis from June 2013 to October 2014 in Department of Orthopedics and Trauma of the first Hospital of Wuhan City. 80 cases were selected. According to the different treatment methods, the patients were divided into experimental group (Chinese medicine group) and control group (western medicine group). There were 40 cases in the experimental group, including 15 males and 25 females. The treatment methods were as follows: after PKP operation, the patients were treated with oral Chinese patent medicine Xianling Gubao capsule calcium regularly (experimental group); 40 cases of control group, including 16 males and 24 females, were treated with alenophosphate calcium on a regular basis after PKP operation (control group: known to be safe and effective). The patients in both groups were followed up to observe and record the JOA scores before and after PKP operation for one month, three months and half a year before and after PKP operation. Pain score (VAS) score by visual analogue score), bone mineral density and other data. The experimental data of each group were compared and analyzed. Results there was no significant difference in JOA score, VAS score and bone mineral density (BMD) between the two groups before and after PKP operation for one month and three months (P0.05). Conclusion Xianling Gubao combined with PKP technique is effective and safe in the treatment of senile osteoporotic spinal compression fracture.
【學位授予單位】：湖北中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2015
【分類號】：R687.3

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