【摘要】：目的觀察活血利水法對大面積腦梗死去骨瓣減壓術后患者神經功能的影響。方法將60例腦梗死術后患者隨機分為對照組和治療組(各30例),均給予常規(guī)西藥治療,治療組加服活血利水方藥治療,療程14天。觀察兩組治療前后神經功能缺損程度(NIHSS)評分,血清超氧化物歧化酶(SOD)和脂質過氧化物(LPO)含量變化。結果治療后,兩組NIHSS評分均較治療前降低(P0.05,P0.01),且治療組低于對照組(P0.01)。治療后,兩組LPO含量均較治療前降低(P0.01),且治療組低于對照組(P0.01);兩組SOD含量均較治療前升高(P0.01),且治療組高于對照組(P0.01)。結論活血利水法可通過抗氧化和清除氧自由基作用改善腦梗死術后患者神經功能。
[Abstract]:Objective to observe the effect of activating blood circulation and promoting water therapy on nerve function of patients with large area cerebral infarction after decompression of bone flap. Methods 60 patients with cerebral infarction after operation were randomly divided into control group and treatment group (30 cases each), all of them were treated with routine western medicine, the treatment group was treated with Huoxue Lishui prescription for 14 days. The (NIHSS) score, serum superoxide dismutase (SOD) and lipid peroxide (LPO) content were observed before and after treatment. Results after treatment, the NIHSS scores in both groups were lower than those before treatment (P0.05, P0.01), and those in the treatment group were lower than those in the control group (P0.01). After treatment, the content of LPO in both groups was lower than that before treatment (P0.01), and the content of SOD in the treatment group was lower than that in the control group (P0.01), and the content of SOD in both groups was higher than that in the control group (P0.01). Conclusion the method of activating blood circulation and promoting water can improve the neurological function of patients with cerebral infarction after operation by anti-oxidation and scavenging oxygen free radical.
【作者單位】： 上海中醫(yī)藥大學附屬曙光醫(yī)院神經外科;
【基金】：上海市高級中西醫(yī)結合人才培養(yǎng)項目(ZYSNXD012-RC-ZXY001)
【分類號】：R651.12

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本文編號：2356232